Application of ectoine in diseases of the skin and mucous membranes

Ectoine is an organic chemical compound from the group of amino acids, produced by microorganisms to protect cells and their organelles from the adverse effects of the external environment. It has a wide range of applications in dermatology, allergy, laryngology, and ophthalmology. Additionally, ong...

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Main Authors: Piotr Kuna, Dominika Ochab-Krupnik, Anna Mościcka, Piotr Łacwik
Format: Article
Language:English
Published: Termedia Publishing House 2024-06-01
Series:Alergologia Polska
Subjects:
Online Access:https://www.termedia.pl/Application-of-ectoine-in-diseases-of-the-skin-and-mucous-membranes,123,54252,1,1.html
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author Piotr Kuna
Dominika Ochab-Krupnik
Anna Mościcka
Piotr Łacwik
author_facet Piotr Kuna
Dominika Ochab-Krupnik
Anna Mościcka
Piotr Łacwik
author_sort Piotr Kuna
collection DOAJ
description Ectoine is an organic chemical compound from the group of amino acids, produced by microorganisms to protect cells and their organelles from the adverse effects of the external environment. It has a wide range of applications in dermatology, allergy, laryngology, and ophthalmology. Additionally, ongoing research shows its potential in pulmonary, gastroenterological, and neurological treatment. Ectoine has been shown to have a protective and moisturizing effect on the skin, making it widely used in both the cosmetic and pharmaceutical industries. It has anti-inflammatory and antioxidant properties, which can support skin protection against damage caused by UVA, UVB, visible and infrared light, environmental pollution, or other potentially harmful factors. Ectoine has also been found to have a beneficial effect on the stability of cell membranes and increases their fluidity. It has been shown to have a positive effect on the stability of DNA helix, increases the temperature resistance of DNA polymerase, and lowers the melting temperature of the double-stranded DNA. In addition it reduces oxidative stress and protects nucleic acids from reactive oxygen forms. Ongoing trials confirming its supportive role in several inflammatory conditions are available, including, but not limited to upper respiratory tract infections, allergic rhinitis, chronic sinusitis, asthma, chronic obstructive pulmonary disease and ocular conditions. It is already available in various practical forms, such as cremes, gels, nasal and pharyngeal sprays and lozenges. The growing body of research suggests further applications, making ectoine a potential key player in supportive treatment of both chronic and acute inflammatory conditions.
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publishDate 2024-06-01
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series Alergologia Polska
spelling doaj-art-c4608830063048278c4c2199ee5f45e72025-01-27T10:34:44ZengTermedia Publishing HouseAlergologia Polska2353-38542391-60522024-06-0111217317910.5114/pja.2024.14035454252Application of ectoine in diseases of the skin and mucous membranesPiotr KunaDominika Ochab-KrupnikAnna MościckaPiotr ŁacwikEctoine is an organic chemical compound from the group of amino acids, produced by microorganisms to protect cells and their organelles from the adverse effects of the external environment. It has a wide range of applications in dermatology, allergy, laryngology, and ophthalmology. Additionally, ongoing research shows its potential in pulmonary, gastroenterological, and neurological treatment. Ectoine has been shown to have a protective and moisturizing effect on the skin, making it widely used in both the cosmetic and pharmaceutical industries. It has anti-inflammatory and antioxidant properties, which can support skin protection against damage caused by UVA, UVB, visible and infrared light, environmental pollution, or other potentially harmful factors. Ectoine has also been found to have a beneficial effect on the stability of cell membranes and increases their fluidity. It has been shown to have a positive effect on the stability of DNA helix, increases the temperature resistance of DNA polymerase, and lowers the melting temperature of the double-stranded DNA. In addition it reduces oxidative stress and protects nucleic acids from reactive oxygen forms. Ongoing trials confirming its supportive role in several inflammatory conditions are available, including, but not limited to upper respiratory tract infections, allergic rhinitis, chronic sinusitis, asthma, chronic obstructive pulmonary disease and ocular conditions. It is already available in various practical forms, such as cremes, gels, nasal and pharyngeal sprays and lozenges. The growing body of research suggests further applications, making ectoine a potential key player in supportive treatment of both chronic and acute inflammatory conditions.https://www.termedia.pl/Application-of-ectoine-in-diseases-of-the-skin-and-mucous-membranes,123,54252,1,1.htmldermatology allergy atopic dermatitis cell membrane stabilization ectoine
spellingShingle Piotr Kuna
Dominika Ochab-Krupnik
Anna Mościcka
Piotr Łacwik
Application of ectoine in diseases of the skin and mucous membranes
Alergologia Polska
dermatology
allergy
atopic dermatitis
cell membrane stabilization
ectoine
title Application of ectoine in diseases of the skin and mucous membranes
title_full Application of ectoine in diseases of the skin and mucous membranes
title_fullStr Application of ectoine in diseases of the skin and mucous membranes
title_full_unstemmed Application of ectoine in diseases of the skin and mucous membranes
title_short Application of ectoine in diseases of the skin and mucous membranes
title_sort application of ectoine in diseases of the skin and mucous membranes
topic dermatology
allergy
atopic dermatitis
cell membrane stabilization
ectoine
url https://www.termedia.pl/Application-of-ectoine-in-diseases-of-the-skin-and-mucous-membranes,123,54252,1,1.html
work_keys_str_mv AT piotrkuna applicationofectoineindiseasesoftheskinandmucousmembranes
AT dominikaochabkrupnik applicationofectoineindiseasesoftheskinandmucousmembranes
AT annamoscicka applicationofectoineindiseasesoftheskinandmucousmembranes
AT piotrłacwik applicationofectoineindiseasesoftheskinandmucousmembranes