DNA Damage and Repair in Glioblastoma: Emerging Therapeutic Perspectives

DNA Damage and Repair in Glioblastoma: Emerging Therapeutic Perspectives

Aggressive and therapy-resistant glioblastoma is among the most lethal malignant tumors in humans. Complete surgical resection is often unachievable; therefore, combination chemoradiotherapy is used to target tumor cells residual beyond the resection margin. This approach induces DNA damage in tumor...

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Bibliographic Details
Main Authors: I. F. Gareev, O. A. Beylerli, S. A. Roumiantsev
Format: Article
Language:English
Published: Bashkir State Medical University 2025-07-01
Series:Креативная хирургия и онкология
Subjects:
glioblastoma
dna repair
dna damage
oncogenesis
chemoradiotherapy
metabolism
cancer stem cells
ddr inhibitors
personalized medicine
Online Access:https://www.surgonco.ru/jour/article/view/1085
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