Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis
Renal tumours in infants and children, ranging from benign to highly malignant, present a significant medical challenge and constitute approximately 3% of all kidney tumours in neonates. This study focuses on congenital mesoblastic nephroma (CMN), the most common renal tumour in neonates. We prese...
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Liaquat National Hospital and Medical College
2025-04-01
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| Series: | Journal of Liaquat National Hospital |
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| Online Access: | https://journals.lnh.edu.pk/jlnh/pdf/f8676fdd-f634-4260-ab10-8bee37e864be.pdf |
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| author | Hina Yousuf Aisha Bakhtiar |
| author_facet | Hina Yousuf Aisha Bakhtiar |
| author_sort | Hina Yousuf |
| collection | DOAJ |
| description | Renal tumours in infants and children, ranging from benign to highly malignant, present a significant medical challenge and constitute
approximately 3% of all kidney tumours in neonates. This study focuses on congenital mesoblastic nephroma (CMN), the most common
renal tumour in neonates. We present a case of a full-term neonate born with a palpable abdominal mass, diagnosed as the cellular subtype of
CMN. Typically benign, CMN often appears as a symptomless abdominal mass without cystic elements. The neonate underwent a radical left
nephroureterectomy, and a histopathological examination confirmed the diagnosis.
Despite its generally benign nature, CMN can lead to serious complications, necessitating early surgical intervention. Our case, 18 months
post-operation, shows no evidence of recurrence, underscoring the importance of regular surveillance in managing this rare renal tumour in
neonates. This review discusses the diagnostic modalities, subtypes, genetic implications, and varying clinical outcomes associated with CMN,
contributing to the understanding and management of this rare pediatric condition. |
| format | Article |
| id | doaj-art-c4545f673dad4fd69d91a8e6e9c0f97e |
| institution | DOAJ |
| issn | 2959-1805 2960-2963 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Liaquat National Hospital and Medical College |
| record_format | Article |
| series | Journal of Liaquat National Hospital |
| spelling | doaj-art-c4545f673dad4fd69d91a8e6e9c0f97e2025-08-20T02:55:35ZengLiaquat National Hospital and Medical CollegeJournal of Liaquat National Hospital2959-18052960-29632025-04-0131646710.37184/jlnh.2959-1805.2.19Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed AnalysisHina Yousuf0Aisha Bakhtiar1Liaquat National Hospital and Medical College, Karachi, PakistanLiaquat National Hospital and Medical College, Karachi, PakistanRenal tumours in infants and children, ranging from benign to highly malignant, present a significant medical challenge and constitute approximately 3% of all kidney tumours in neonates. This study focuses on congenital mesoblastic nephroma (CMN), the most common renal tumour in neonates. We present a case of a full-term neonate born with a palpable abdominal mass, diagnosed as the cellular subtype of CMN. Typically benign, CMN often appears as a symptomless abdominal mass without cystic elements. The neonate underwent a radical left nephroureterectomy, and a histopathological examination confirmed the diagnosis. Despite its generally benign nature, CMN can lead to serious complications, necessitating early surgical intervention. Our case, 18 months post-operation, shows no evidence of recurrence, underscoring the importance of regular surveillance in managing this rare renal tumour in neonates. This review discusses the diagnostic modalities, subtypes, genetic implications, and varying clinical outcomes associated with CMN, contributing to the understanding and management of this rare pediatric condition.https://journals.lnh.edu.pk/jlnh/pdf/f8676fdd-f634-4260-ab10-8bee37e864be.pdfcongenital mesoblastic nephroma (cmn)nephrectomycellular cmnetv6infantile tumour |
| spellingShingle | Hina Yousuf Aisha Bakhtiar Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis Journal of Liaquat National Hospital congenital mesoblastic nephroma (cmn) nephrectomy cellular cmn etv6 infantile tumour |
| title | Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis |
| title_full | Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis |
| title_fullStr | Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis |
| title_full_unstemmed | Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis |
| title_short | Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis |
| title_sort | congenital mesoblastic nephroma at birth a case report and detailed analysis |
| topic | congenital mesoblastic nephroma (cmn) nephrectomy cellular cmn etv6 infantile tumour |
| url | https://journals.lnh.edu.pk/jlnh/pdf/f8676fdd-f634-4260-ab10-8bee37e864be.pdf |
| work_keys_str_mv | AT hinayousuf congenitalmesoblasticnephromaatbirthacasereportanddetailedanalysis AT aishabakhtiar congenitalmesoblasticnephromaatbirthacasereportanddetailedanalysis |