Congenital Mesoblastic Nephroma at Birth: A Case Report and Detailed Analysis

Renal tumours in infants and children, ranging from benign to highly malignant, present a significant medical challenge and constitute approximately 3% of all kidney tumours in neonates. This study focuses on congenital mesoblastic nephroma (CMN), the most common renal tumour in neonates. We prese...

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Bibliographic Details
Main Authors: Hina Yousuf, Aisha Bakhtiar
Format: Article
Language:English
Published: Liaquat National Hospital and Medical College 2025-04-01
Series:Journal of Liaquat National Hospital
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Online Access:https://journals.lnh.edu.pk/jlnh/pdf/f8676fdd-f634-4260-ab10-8bee37e864be.pdf
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Summary:Renal tumours in infants and children, ranging from benign to highly malignant, present a significant medical challenge and constitute approximately 3% of all kidney tumours in neonates. This study focuses on congenital mesoblastic nephroma (CMN), the most common renal tumour in neonates. We present a case of a full-term neonate born with a palpable abdominal mass, diagnosed as the cellular subtype of CMN. Typically benign, CMN often appears as a symptomless abdominal mass without cystic elements. The neonate underwent a radical left nephroureterectomy, and a histopathological examination confirmed the diagnosis. Despite its generally benign nature, CMN can lead to serious complications, necessitating early surgical intervention. Our case, 18 months post-operation, shows no evidence of recurrence, underscoring the importance of regular surveillance in managing this rare renal tumour in neonates. This review discusses the diagnostic modalities, subtypes, genetic implications, and varying clinical outcomes associated with CMN, contributing to the understanding and management of this rare pediatric condition.
ISSN:2959-1805
2960-2963