Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)

This study aims to provide a set of experimentally determined forces needed for gripping operations related to a robotically manipulated microliter manual pipette. The experiments are conducted within the scope of automated sample processing for polymerase chain reaction (PCR) analysis in small-size...

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Main Authors: Melania-Olivia Sandu, Valentin Ciupe, Corina-Mihaela Gruescu, Robert Kristof, Carmen Sticlaru, Elida-Gabriela Tulcan
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Robotics
Subjects:
Online Access:https://www.mdpi.com/2218-6581/14/1/2
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author Melania-Olivia Sandu
Valentin Ciupe
Corina-Mihaela Gruescu
Robert Kristof
Carmen Sticlaru
Elida-Gabriela Tulcan
author_facet Melania-Olivia Sandu
Valentin Ciupe
Corina-Mihaela Gruescu
Robert Kristof
Carmen Sticlaru
Elida-Gabriela Tulcan
author_sort Melania-Olivia Sandu
collection DOAJ
description This study aims to provide a set of experimentally determined forces needed for gripping operations related to a robotically manipulated microliter manual pipette. The experiments are conducted within the scope of automated sample processing for polymerase chain reaction (PCR) analysis in small-sized to medium-sized laboratories where dedicated automated equipment is absent and where procedures are carried out manually. Automation is justified by the requirement for increased efficiency and to eliminate possible errors generated by lab technicians. The test system comprises an industrial robot; a dedicated custom gripper assembly necessary for the pipette; pipetting tips; and mechanical holders for tubes with chemical substances and genetic material. The selected approach is to measure forces using the robot’s built-in force–torque sensor while controlling and limiting the pipette’s gripping force and the robot’s pushing force. Because the manipulation of different materials requires the attachment and discarding of tips to and from the pipette, the operator’s perceived tip release force is also considered.
format Article
id doaj-art-c4542e1f7e24498691ef3079e3c8fa34
institution Kabale University
issn 2218-6581
language English
publishDate 2024-12-01
publisher MDPI AG
record_format Article
series Robotics
spelling doaj-art-c4542e1f7e24498691ef3079e3c8fa342025-01-24T13:48:22ZengMDPI AGRobotics2218-65812024-12-01141210.3390/robotics14010002Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)Melania-Olivia Sandu0Valentin Ciupe1Corina-Mihaela Gruescu2Robert Kristof3Carmen Sticlaru4Elida-Gabriela Tulcan5Department of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaDepartment of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaDepartment of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaDepartment of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaDepartment of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaDepartment of Mechatronics, Politehnica University of Timisoara, 300006 Timișoara, RomaniaThis study aims to provide a set of experimentally determined forces needed for gripping operations related to a robotically manipulated microliter manual pipette. The experiments are conducted within the scope of automated sample processing for polymerase chain reaction (PCR) analysis in small-sized to medium-sized laboratories where dedicated automated equipment is absent and where procedures are carried out manually. Automation is justified by the requirement for increased efficiency and to eliminate possible errors generated by lab technicians. The test system comprises an industrial robot; a dedicated custom gripper assembly necessary for the pipette; pipetting tips; and mechanical holders for tubes with chemical substances and genetic material. The selected approach is to measure forces using the robot’s built-in force–torque sensor while controlling and limiting the pipette’s gripping force and the robot’s pushing force. Because the manipulation of different materials requires the attachment and discarding of tips to and from the pipette, the operator’s perceived tip release force is also considered.https://www.mdpi.com/2218-6581/14/1/2robotic handlingforce measurementpipetting device
spellingShingle Melania-Olivia Sandu
Valentin Ciupe
Corina-Mihaela Gruescu
Robert Kristof
Carmen Sticlaru
Elida-Gabriela Tulcan
Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
Robotics
robotic handling
force measurement
pipetting device
title Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
title_full Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
title_fullStr Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
title_full_unstemmed Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
title_short Determining the Proper Force Parameters for Robotized Pipetting Devices Used in Automated Polymerase Chain Reaction (PCR)
title_sort determining the proper force parameters for robotized pipetting devices used in automated polymerase chain reaction pcr
topic robotic handling
force measurement
pipetting device
url https://www.mdpi.com/2218-6581/14/1/2
work_keys_str_mv AT melaniaoliviasandu determiningtheproperforceparametersforrobotizedpipettingdevicesusedinautomatedpolymerasechainreactionpcr
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AT corinamihaelagruescu determiningtheproperforceparametersforrobotizedpipettingdevicesusedinautomatedpolymerasechainreactionpcr
AT robertkristof determiningtheproperforceparametersforrobotizedpipettingdevicesusedinautomatedpolymerasechainreactionpcr
AT carmensticlaru determiningtheproperforceparametersforrobotizedpipettingdevicesusedinautomatedpolymerasechainreactionpcr
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