IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.

Background Physical and psychological factors, like wrong attitudes and behaviours, can negatively influence health outcomes of the patients receiving allogeneic hematopoietic stem cell transplantation (AHSCT). Educational interventions aiming to improve knowledge on side effects, risks, complica...

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Main Authors: Marco Cioce, Franziska Michaela Lohmeyer, Rossana Moroni, Marinella Magini, Alessandra Giraldi, Paola Garau, Maria Carola Gifuni, Vezio Savoia, Danilo Celli, Stefano Botti, Gianpaolo Gargiulo, Francesca Bonifazi, Fabio Ciceri, Ivana Serra, Maurizio Zega, Simona Sica, Andrea Bacigalupo, Valerio De Stefano, Umberto Moscato
Format: Article
Language:English
Published: PAGEPress Publications 2020-08-01
Series:Mediterranean Journal of Hematology and Infectious Diseases
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Online Access:https://www.mjhid.org/index.php/mjhid/article/view/4305
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author Marco Cioce
Franziska Michaela Lohmeyer
Rossana Moroni
Marinella Magini
Alessandra Giraldi
Paola Garau
Maria Carola Gifuni
Vezio Savoia
Danilo Celli
Stefano Botti
Gianpaolo Gargiulo
Francesca Bonifazi
Fabio Ciceri
Ivana Serra
Maurizio Zega
Simona Sica
Andrea Bacigalupo
Valerio De Stefano
Umberto Moscato
author_facet Marco Cioce
Franziska Michaela Lohmeyer
Rossana Moroni
Marinella Magini
Alessandra Giraldi
Paola Garau
Maria Carola Gifuni
Vezio Savoia
Danilo Celli
Stefano Botti
Gianpaolo Gargiulo
Francesca Bonifazi
Fabio Ciceri
Ivana Serra
Maurizio Zega
Simona Sica
Andrea Bacigalupo
Valerio De Stefano
Umberto Moscato
author_sort Marco Cioce
collection DOAJ
description Background Physical and psychological factors, like wrong attitudes and behaviours, can negatively influence health outcomes of the patients receiving allogeneic hematopoietic stem cell transplantation (AHSCT). Educational interventions aiming to improve knowledge on side effects, risks, complications and preventive behaviour can reduce psychological distress, and improve quality of life (QoL). We aimed to compare a standard approach with therapeutic patient education (TPE) to analyse the impact on AHSCT patients’ QoL, psychological distress and knowledge of AHSCT side effects, risks complications and preventive behaviour. Material and methods A prospective interventional study was conducted analysing data of 36 patients who received one of two different educational approaches, which were a standard approach (not-exposed) or TPE (exposed). Results In the exposed group QoL improved 14 days after transplantation (42.2 vs 25.6; p<0.03) and at time of discharge (36.6 vs 54.4; p<0.005). Anxiety and depression was better controlled in the exposed group, both at hospitalization and discharge (anxiety: 48.1 vs 53.2; 46.4 vs 51.6. p<0.04; depression: 49 vs 55.3; 48 vs 54.3 , p<0.03). Knowledge of AHSCT risks and complications improved in exposed patients, both at admission (10.1/15 vs 8/15 correct answers; p<0.01) and discharge (10.7/15 vs 8.8/15 correct answer; p<0.03). Conclusion The TPE for AHSCT patients improved knowledge, reduced anxiety and depression, which consequently increasing QoL. Therefore, we recommend our approach to further engage patients in the treatment plan, which should specifically take place prior to AHSCT initiation.
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spelling doaj-art-c45409ff10734dd9a2ab15e3a90f8ece2025-08-20T01:47:51ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062020-08-0112110.4084/mjhid.2020.067IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.Marco Cioce0Franziska Michaela LohmeyerRossana MoroniMarinella MaginiAlessandra GiraldiPaola GarauMaria Carola GifuniVezio SavoiaDanilo CelliStefano BottiGianpaolo GargiuloFrancesca BonifaziFabio CiceriIvana SerraMaurizio ZegaSimona SicaAndrea BacigalupoValerio De StefanoUmberto Moscato{'en_US': 'Fondazione PoliclinicoUniversitario Agostino Gemelli IRCCS Roma'}Background Physical and psychological factors, like wrong attitudes and behaviours, can negatively influence health outcomes of the patients receiving allogeneic hematopoietic stem cell transplantation (AHSCT). Educational interventions aiming to improve knowledge on side effects, risks, complications and preventive behaviour can reduce psychological distress, and improve quality of life (QoL). We aimed to compare a standard approach with therapeutic patient education (TPE) to analyse the impact on AHSCT patients’ QoL, psychological distress and knowledge of AHSCT side effects, risks complications and preventive behaviour. Material and methods A prospective interventional study was conducted analysing data of 36 patients who received one of two different educational approaches, which were a standard approach (not-exposed) or TPE (exposed). Results In the exposed group QoL improved 14 days after transplantation (42.2 vs 25.6; p<0.03) and at time of discharge (36.6 vs 54.4; p<0.005). Anxiety and depression was better controlled in the exposed group, both at hospitalization and discharge (anxiety: 48.1 vs 53.2; 46.4 vs 51.6. p<0.04; depression: 49 vs 55.3; 48 vs 54.3 , p<0.03). Knowledge of AHSCT risks and complications improved in exposed patients, both at admission (10.1/15 vs 8/15 correct answers; p<0.01) and discharge (10.7/15 vs 8.8/15 correct answer; p<0.03). Conclusion The TPE for AHSCT patients improved knowledge, reduced anxiety and depression, which consequently increasing QoL. Therefore, we recommend our approach to further engage patients in the treatment plan, which should specifically take place prior to AHSCT initiation.https://www.mjhid.org/index.php/mjhid/article/view/4305therapeutic patient education, allogeneic hematopoietic stem cell transplantation, quality of life, psychological support, patient engagement
spellingShingle Marco Cioce
Franziska Michaela Lohmeyer
Rossana Moroni
Marinella Magini
Alessandra Giraldi
Paola Garau
Maria Carola Gifuni
Vezio Savoia
Danilo Celli
Stefano Botti
Gianpaolo Gargiulo
Francesca Bonifazi
Fabio Ciceri
Ivana Serra
Maurizio Zega
Simona Sica
Andrea Bacigalupo
Valerio De Stefano
Umberto Moscato
IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
Mediterranean Journal of Hematology and Infectious Diseases
therapeutic patient education, allogeneic hematopoietic stem cell transplantation, quality of life, psychological support, patient engagement
title IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
title_full IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
title_fullStr IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
title_full_unstemmed IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
title_short IMPACT OF EDUCATIONAL INTERVENTIONS ON PSYCHOLOGICAL DISTRESS DURING ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: A RANDOMIZED STUDY.
title_sort impact of educational interventions on psychological distress during allogeneic hematopoietic stem cell transplantation a randomized study
topic therapeutic patient education, allogeneic hematopoietic stem cell transplantation, quality of life, psychological support, patient engagement
url https://www.mjhid.org/index.php/mjhid/article/view/4305
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