Multi-omic integration of single-cell data uncovers methylation profiles of super-enhancers in skeletal muscle stem cells
Abstract Introduction Skeletal muscle stem cells (MuSCs) have strong regenerative abilities, but as we age, their ability to regenerate decreases, leading to a decline in muscle function. Although the methylation reprogramming of super-enhancers (SEs) plays a pivotal role in regulating gene expressi...
Saved in:
| Main Authors: | Anyu Zeng, Hailong Liu, Shuling He, Xuming Luo, Zhiqi Zhang, Ming Fu, Baoxi Yu |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | Epigenetics & Chromatin |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13072-025-00619-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Exercise promotes skeletal muscle growth in adolescents via modulating Mettl3-mediated m6A methylation of MyoD in muscle satellite cells
by: Shujing Feng, et al.
Published: (2024-12-01) -
The SUV39 Family of H3K9 Methyltransferases in Skeletal Muscle Stem Cells
by: Pauline Garcia, et al.
Published: (2025-06-01) -
Physical exercise and epigenetic modifications in skeletal muscle, brain, and heart
by: Xi Zheng, et al.
Published: (2025-03-01) -
Exercise-induced methylation of the Serhl2 promoter and implication for lipid metabolism in rat skeletal muscle
by: Mutsumi Katayama, et al.
Published: (2025-02-01) -
Abnormal methylation of Mill1 gene regulates osteogenic differentiation involved in various phenotypes of skeletal fluorosis in rats and methionine intervention
by: Niannian Chen, et al.
Published: (2025-01-01)