Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Pharmacology Study for Targeting Glioblastoma Management

<b>Objective</b>: This study aims to develop an intranasal (IN) delivery system for glioblastoma multiforme (GBM) management using repurposed superparamagnetic iron-oxide (SPION) loaded with atorvastatin (ATO)-nanostructured lipid carrier (NLC). <b>Methods</b>: Emulsification...

Full description

Saved in:

Bibliographic Details
Main Authors:	Kristina Zarif Attalla, Doaa H. Hassan, Mahmoud H. Teaima, Carol Yousry, Mohamed A. El-Nabarawi, Mohamed A. Said, Sammar Fathy Elhabal
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Series:	Pharmaceuticals
Subjects:	intranasal hydrogel nanocarriers atorvastatin superparamagnetic iron oxide glioblastoma multiforme enhanced permeation and retention effect and brain targeting
Online Access:	https://www.mdpi.com/1424-8247/18/3/421
Tags:	Add Tag No Tags, Be the first to tag this record!

Be the first to leave a comment!

Enhanced Intranasal Delivery of Atorvastatin via Superparamagnetic Iron-Oxide-Loaded Nanocarriers: Cytotoxicity and Inflammation Evaluation and In Vivo, In Silico, and Network Pharmacology Study for Targeting Glioblastoma Management

Similar Items