Towards understanding the gliotoxin detoxification mechanism: in vivo thiomethylation protects yeast from gliotoxin cytotoxicity
Gliotoxin (GT) is a mycotoxin produced by some species of ascomycete fungi including the opportunistic human pathogen Aspergillus fumigatus. In order to produce GT the host organism needs to have evolved a self-protection mechanism. GT contains a redox-cycling disulfide bridge that is important in m...
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| Main Authors: | Elizabeth B. Smith, Stephen K. Dolan, David A. Fitzpatrick, Sean Doyle, Gary W. Jones |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Shared Science Publishers OG
2016-02-01
|
| Series: | Microbial Cell |
| Subjects: | |
| Online Access: | http://microbialcell.com/researcharticles/towards-understanding-the-gliotoxin-detoxification-mechanism-in-vivo-thiomethylation-protects-yeast-from-gliotoxin-cytotoxicity/ |
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