Aging-related changes of miR-23b-3p expression in extracellular vesicles from mesenchymal stromal cells affect TGFBR3 signaling
Abstract Extracellular vesicles (EVs), which carry biological mediators such as microRNAs (miRNAs) and cytokines, play a crucial role in regulating recipient tissues and are considered a key mechanism of action in cell therapy. However, it has been found that cellular aging in donor cells significan...
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| Main Authors: | Maki Itokazu, Toshiyuki Takehara, Kensuke Toriumi, Natsumi Iwawaki, Tatsufumi Mori, Yuta Ondoera, Yuji Higashimoto, Koji Goto, Hidekazu Yamada, Takeshi Teramura |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-06982-y |
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