Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction
Ceftriaxone (CTRX) is known to cause reversible biliary stones/sludge, which is called biliary pseudolithiasis. We report two rare cases of biliary obstruction by pseudolithiasis shortly after completing CTRX treatment. Stones and sludge, which had not been detected before CTRX administration, appea...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2017/3835825 |
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| author | Yasuhiro Doi Yasushi Takii Hiroyuki Ito Norihiko Jingu Kentaro To Sinichiro Kimura Koichi Kimura Kensaku Sanefuji Hirofumi Ikeda Sayaka Tachibana Takeshi Otsuka |
| author_facet | Yasuhiro Doi Yasushi Takii Hiroyuki Ito Norihiko Jingu Kentaro To Sinichiro Kimura Koichi Kimura Kensaku Sanefuji Hirofumi Ikeda Sayaka Tachibana Takeshi Otsuka |
| author_sort | Yasuhiro Doi |
| collection | DOAJ |
| description | Ceftriaxone (CTRX) is known to cause reversible biliary stones/sludge, which is called biliary pseudolithiasis. We report two rare cases of biliary obstruction by pseudolithiasis shortly after completing CTRX treatment. Stones and sludge, which had not been detected before CTRX administration, appeared in the gallbladder and common bile duct and led to biliary obstruction and acute cholangitis. The obstructions were successfully treated with endoscopic retrograde biliary drainage and endoscopic sphincterotomy. CTRX-induced biliary pseudolithiasis has been reported mainly in children and adolescents but is also seen in adults with similar incidence rate. Although CTRX-induced biliary pseudolithiasis is usually asymptomatic and disappears spontaneously after discontinuing the drug, some patients develop biliary obstruction. Endoscopic managements should be considered in such cases. |
| format | Article |
| id | doaj-art-c4382ee45e3f4f3998992beea90b9d3e |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-c4382ee45e3f4f3998992beea90b9d3e2025-02-03T05:47:35ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/38358253835825Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary ObstructionYasuhiro Doi0Yasushi Takii1Hiroyuki Ito2Norihiko Jingu3Kentaro To4Sinichiro Kimura5Koichi Kimura6Kensaku Sanefuji7Hirofumi Ikeda8Sayaka Tachibana9Takeshi Otsuka10Department of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Surgery, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Surgery, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Nephrology, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Nephrology, Munakata Medical Association Hospital, Fukuoka, JapanDepartment of Internal Medicine, Munakata Medical Association Hospital, Fukuoka, JapanCeftriaxone (CTRX) is known to cause reversible biliary stones/sludge, which is called biliary pseudolithiasis. We report two rare cases of biliary obstruction by pseudolithiasis shortly after completing CTRX treatment. Stones and sludge, which had not been detected before CTRX administration, appeared in the gallbladder and common bile duct and led to biliary obstruction and acute cholangitis. The obstructions were successfully treated with endoscopic retrograde biliary drainage and endoscopic sphincterotomy. CTRX-induced biliary pseudolithiasis has been reported mainly in children and adolescents but is also seen in adults with similar incidence rate. Although CTRX-induced biliary pseudolithiasis is usually asymptomatic and disappears spontaneously after discontinuing the drug, some patients develop biliary obstruction. Endoscopic managements should be considered in such cases.http://dx.doi.org/10.1155/2017/3835825 |
| spellingShingle | Yasuhiro Doi Yasushi Takii Hiroyuki Ito Norihiko Jingu Kentaro To Sinichiro Kimura Koichi Kimura Kensaku Sanefuji Hirofumi Ikeda Sayaka Tachibana Takeshi Otsuka Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction Case Reports in Medicine |
| title | Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction |
| title_full | Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction |
| title_fullStr | Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction |
| title_full_unstemmed | Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction |
| title_short | Usefulness of Endoscopic Managements in Patients with Ceftriaxone-Induced Pseudolithiasis Causing Biliary Obstruction |
| title_sort | usefulness of endoscopic managements in patients with ceftriaxone induced pseudolithiasis causing biliary obstruction |
| url | http://dx.doi.org/10.1155/2017/3835825 |
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