Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature
Comorbidity depression – diabetes is a common condition and is often associated with complications and high mortality. Both of these conditions are due to genetic predispositions associated with environmental factors. Many mechanisms explain the occurrence of this comorbidity. Two are the most studi...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Endocrine and Metabolic Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666396124000578 |
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| _version_ | 1850219634306842624 |
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| author | Roland Muyisa Muhindo |
| author_facet | Roland Muyisa Muhindo |
| author_sort | Roland Muyisa Muhindo |
| collection | DOAJ |
| description | Comorbidity depression – diabetes is a common condition and is often associated with complications and high mortality. Both of these conditions are due to genetic predispositions associated with environmental factors. Many mechanisms explain the occurrence of this comorbidity. Two are the most studied: the involvement of oxidative stress and chronic inflammation. For the management, the management of depression in diabetics does not consist of a simple combination of antidepressants with antidiabetics but global management including medicinal and non-drug means. New drugs targeting NRH2 are in development. They would act on comorbidity depression – diabetes at the same time. |
| format | Article |
| id | doaj-art-c43365ecdeb14f1497519e76582153a2 |
| institution | OA Journals |
| issn | 2666-3961 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Endocrine and Metabolic Science |
| spelling | doaj-art-c43365ecdeb14f1497519e76582153a22025-08-20T02:07:19ZengElsevierEndocrine and Metabolic Science2666-39612025-03-011710021310.1016/j.endmts.2024.100213Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literatureRoland Muyisa Muhindo0Catholic University of the Graben, Butembo, Democratic Republic of the CongoComorbidity depression – diabetes is a common condition and is often associated with complications and high mortality. Both of these conditions are due to genetic predispositions associated with environmental factors. Many mechanisms explain the occurrence of this comorbidity. Two are the most studied: the involvement of oxidative stress and chronic inflammation. For the management, the management of depression in diabetics does not consist of a simple combination of antidepressants with antidiabetics but global management including medicinal and non-drug means. New drugs targeting NRH2 are in development. They would act on comorbidity depression – diabetes at the same time.http://www.sciencedirect.com/science/article/pii/S2666396124000578DepressionDiabetesComorbidityEtiopathogenesisManagementUpdates |
| spellingShingle | Roland Muyisa Muhindo Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature Endocrine and Metabolic Science Depression Diabetes Comorbidity Etiopathogenesis Management Updates |
| title | Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature |
| title_full | Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature |
| title_fullStr | Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature |
| title_full_unstemmed | Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature |
| title_short | Etiopathogenesis and management updates on the comorbidity depression – Diabetes: A review of literature |
| title_sort | etiopathogenesis and management updates on the comorbidity depression diabetes a review of literature |
| topic | Depression Diabetes Comorbidity Etiopathogenesis Management Updates |
| url | http://www.sciencedirect.com/science/article/pii/S2666396124000578 |
| work_keys_str_mv | AT rolandmuyisamuhindo etiopathogenesisandmanagementupdatesonthecomorbiditydepressiondiabetesareviewofliterature |