Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil
Dogs act as definitive hosts for several diseases caused by protozoa, some of which are zoonotic. Due to their close contact with humans and other animals, they play a crucial role in the transmission of these diseases. Although infection with Neospora caninum or Leishmania infantum is not a determi...
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| Language: | English |
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Sciendo
2024-12-01
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| Series: | Acta Veterinaria |
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| Online Access: | https://doi.org/10.2478/acve-2024-0040 |
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| author | Sena Bianca Ribas Freitas Maria Sabrina de Freitas Maria Natália de Almeida Arleana do Bom Parto Ferreira de Sousa Valéria Régia Franco |
| author_facet | Sena Bianca Ribas Freitas Maria Sabrina de Freitas Maria Natália de Almeida Arleana do Bom Parto Ferreira de Sousa Valéria Régia Franco |
| author_sort | Sena Bianca Ribas |
| collection | DOAJ |
| description | Dogs act as definitive hosts for several diseases caused by protozoa, some of which are zoonotic. Due to their close contact with humans and other animals, they play a crucial role in the transmission of these diseases. Although infection with Neospora caninum or Leishmania infantum is not a determining factor for another, co-infection with these protozoa can aggravate clinical signs and increase the mortality rate. Though, there are reports of success in the treatment of neosporosis, the prognosis is generally considered unfavorable, especially in young dogs. The objective of this study is to report a case of infection by both protozoa in a dog treated at a university veterinary hospital, highlighting the clinical remission of nervous signs of neosporosis after treatment with the combination of sulfadoxine and clindamycin, followed by reduction of clinical signs of canine leishmaniasis (CanL) with treatment with miltefosine and allopurinol. Despite the worse prognosis for co-infection with N. caninum and L. infantum, the dog presented remission of neurological signs and a reduction in parasite load and clinicopathological signs associated with CanL. |
| format | Article |
| id | doaj-art-c41c64875d6f42d08a38f926a9f6f33c |
| institution | Kabale University |
| issn | 1820-7448 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Acta Veterinaria |
| spelling | doaj-art-c41c64875d6f42d08a38f926a9f6f33c2025-01-02T06:04:11ZengSciendoActa Veterinaria1820-74482024-12-0174457358110.2478/acve-2024-0040Neosporosis and Visceral Leishmaniosis in a Dog in Central–West BrazilSena Bianca Ribas0Freitas Maria Sabrina de1Freitas Maria Natália de2Almeida Arleana do Bom Parto Ferreira de3Sousa Valéria Régia Franco41Universidade Federal de Mato Grosso (UFMT), Programa de Residência Uniprofissional em Medicina Veterinária, Cuiabá, MT, Brasil2Universidade Federal de Mato Grosso (UFMT), Programa de Pós-Graduação em Ciências Veterinárias, Cuiabá, MT, Brasil2Universidade Federal de Mato Grosso (UFMT), Programa de Pós-Graduação em Ciências Veterinárias, Cuiabá, MT, Brasil3Universidade Federal de Mato Grosso (UFMT), Faculdade de Medicina Veterinária (FAVET), Cuiabá, MT, Brasil3Universidade Federal de Mato Grosso (UFMT), Faculdade de Medicina Veterinária (FAVET), Cuiabá, MT, BrasilDogs act as definitive hosts for several diseases caused by protozoa, some of which are zoonotic. Due to their close contact with humans and other animals, they play a crucial role in the transmission of these diseases. Although infection with Neospora caninum or Leishmania infantum is not a determining factor for another, co-infection with these protozoa can aggravate clinical signs and increase the mortality rate. Though, there are reports of success in the treatment of neosporosis, the prognosis is generally considered unfavorable, especially in young dogs. The objective of this study is to report a case of infection by both protozoa in a dog treated at a university veterinary hospital, highlighting the clinical remission of nervous signs of neosporosis after treatment with the combination of sulfadoxine and clindamycin, followed by reduction of clinical signs of canine leishmaniasis (CanL) with treatment with miltefosine and allopurinol. Despite the worse prognosis for co-infection with N. caninum and L. infantum, the dog presented remission of neurological signs and a reduction in parasite load and clinicopathological signs associated with CanL.https://doi.org/10.2478/acve-2024-0040neospora caninumleishmania infantumco-infectionmiltefosine |
| spellingShingle | Sena Bianca Ribas Freitas Maria Sabrina de Freitas Maria Natália de Almeida Arleana do Bom Parto Ferreira de Sousa Valéria Régia Franco Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil Acta Veterinaria neospora caninum leishmania infantum co-infection miltefosine |
| title | Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil |
| title_full | Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil |
| title_fullStr | Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil |
| title_full_unstemmed | Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil |
| title_short | Neosporosis and Visceral Leishmaniosis in a Dog in Central–West Brazil |
| title_sort | neosporosis and visceral leishmaniosis in a dog in central west brazil |
| topic | neospora caninum leishmania infantum co-infection miltefosine |
| url | https://doi.org/10.2478/acve-2024-0040 |
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