Cellular Nutrition in Complex Three-Dimensional Scaffolds: A Comparison between Experiments and Computer Simulations
Studies on bone cell ingrowth into synthetic, porous three-dimensional (3D) implants showed difficulties arising from impaired cellular proliferation and differentiation in the core region of these scaffolds with increasing scaffold volume in vitro. Therefore, we developed an in vitro perfusion cell...
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| Main Authors: | Claudia Bergemann, Patrick Elter, Regina Lange, Volker Weißmann, Harald Hansmann, Ernst-Dieter Klinkenberg, Barbara Nebe |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2015/584362 |
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