Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass

Roux-en-Y gastric bypass (RYGB) is the most common weight loss procedure performed in the US. Gastric bypass–related hyperammonemia (GaBHA) is a potentially fatal entity, characterized by encephalopathy associated with hyperammonemia and various nutritional deficiencies, which can present at variabl...

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Main Authors: Juan D. Salcedo, Jordan S. Goldstein, Jose M. Quinonez, Maria Antonietta Mosetti
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2019/9031087
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author Juan D. Salcedo
Jordan S. Goldstein
Jose M. Quinonez
Maria Antonietta Mosetti
author_facet Juan D. Salcedo
Jordan S. Goldstein
Jose M. Quinonez
Maria Antonietta Mosetti
author_sort Juan D. Salcedo
collection DOAJ
description Roux-en-Y gastric bypass (RYGB) is the most common weight loss procedure performed in the US. Gastric bypass–related hyperammonemia (GaBHA) is a potentially fatal entity, characterized by encephalopathy associated with hyperammonemia and various nutritional deficiencies, which can present at variable time intervals after RYGB. Twenty-five cases of hyperammonemic encephalopathy after bariatric surgery have been previously reported in the literature. We describe the case of a 48-year-old Hispanic woman with no prior history of liver disease, presenting with nonfatal hyperammonemic encephalopathy as a late postoperative complication 20 years after undergoing a RYGB. Hyperammonemic encephalopathy in the absence of known hepatic dysfunction presents a diagnostic dilemma. An early diagnosis and intervention are crucial to decrease morbidity and mortality.
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-c4105229b2c54bfd9544a8cb103989882025-02-03T01:11:33ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/90310879031087Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric BypassJuan D. Salcedo0Jordan S. Goldstein1Jose M. Quinonez2Maria Antonietta Mosetti3Department of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, USADepartment of Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, USAUniversity of Miami Miller School of Medicine, Miami, FL, USADivision of Hospital Medicine, University of Miami Medical Towers, University of Miami Miller School of Medicine, Miami, FL, USARoux-en-Y gastric bypass (RYGB) is the most common weight loss procedure performed in the US. Gastric bypass–related hyperammonemia (GaBHA) is a potentially fatal entity, characterized by encephalopathy associated with hyperammonemia and various nutritional deficiencies, which can present at variable time intervals after RYGB. Twenty-five cases of hyperammonemic encephalopathy after bariatric surgery have been previously reported in the literature. We describe the case of a 48-year-old Hispanic woman with no prior history of liver disease, presenting with nonfatal hyperammonemic encephalopathy as a late postoperative complication 20 years after undergoing a RYGB. Hyperammonemic encephalopathy in the absence of known hepatic dysfunction presents a diagnostic dilemma. An early diagnosis and intervention are crucial to decrease morbidity and mortality.http://dx.doi.org/10.1155/2019/9031087
spellingShingle Juan D. Salcedo
Jordan S. Goldstein
Jose M. Quinonez
Maria Antonietta Mosetti
Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
Case Reports in Gastrointestinal Medicine
title Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
title_full Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
title_fullStr Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
title_full_unstemmed Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
title_short Nonfatal Hyperammonemic Encephalopathy as a Late Complication of Roux-en-Y Gastric Bypass
title_sort nonfatal hyperammonemic encephalopathy as a late complication of roux en y gastric bypass
url http://dx.doi.org/10.1155/2019/9031087
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