Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients
Objective: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fasting glucose with the stage, grade and histological type of cancer and its value in predicting the prognosis of endometrial cancer in diabetic endometrial cancer patients. Study Design: The data of 1...
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Medical Network
2024-04-01
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| Series: | Gynecology Obstetrics & Reproductive Medicine |
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| Online Access: | https://gorm.com.tr/index.php/GORM/article/view/1386 |
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| author | Ayse Rabia Senkaya Sercan Kantarci Suna Yildirim Karaca Muzaffer Sanci |
| author_facet | Ayse Rabia Senkaya Sercan Kantarci Suna Yildirim Karaca Muzaffer Sanci |
| author_sort | Ayse Rabia Senkaya |
| collection | DOAJ |
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Objective: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fasting glucose with the stage, grade and histological type of cancer and its value in predicting the prognosis of endometrial cancer in diabetic endometrial cancer patients.
Study Design: The data of 138 endometrial cancer patients with diabetes who met the study criteria were analyzed. Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy and radiotherapy data.
Results: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion (p=0.02). While there was no significant correlation between endometrial thickness and HbA1c, a low positive correlation was found between the fasting glucose value (r=0.191, p=0.025)
Conclusions: The higher rate of lymphovascular invasion in patients with high HbA1c value alone is insufficient in determining the prognosis when other parameters are considered.
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| format | Article |
| id | doaj-art-c3f16d838c1140b39b7a697a9d593834 |
| institution | Kabale University |
| issn | 1300-4751 2602-4918 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Medical Network |
| record_format | Article |
| series | Gynecology Obstetrics & Reproductive Medicine |
| spelling | doaj-art-c3f16d838c1140b39b7a697a9d5938342025-02-11T21:18:16ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512602-49182024-04-0130110.21613/GORM.2023.1386Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer PatientsAyse Rabia Senkaya0Sercan Kantarci1Suna Yildirim Karaca2Muzaffer Sanci3İzmir Bakırçay University Faculty of MedicineUniversity of Health Sciences Tepecik Training and Research HospitalUniversity of Health Sciences Tepecik Training and Research HospitalUniversity of Health Sciences Tepecik Training and Research Hospital Objective: Our aim in this study is to examine the relationship of hemoglobin A1c (HbA1c) and fasting glucose with the stage, grade and histological type of cancer and its value in predicting the prognosis of endometrial cancer in diabetic endometrial cancer patients. Study Design: The data of 138 endometrial cancer patients with diabetes who met the study criteria were analyzed. Hemoglobin A1c levels and fasting glucose were compared with cancer stage, grade, histological type, lymphovascular invasion, chemotherapy and radiotherapy data. Results: A statistically significant difference was found between the groups in terms of HbA1c values only according to the lymphovascular invasion (p=0.02). While there was no significant correlation between endometrial thickness and HbA1c, a low positive correlation was found between the fasting glucose value (r=0.191, p=0.025) Conclusions: The higher rate of lymphovascular invasion in patients with high HbA1c value alone is insufficient in determining the prognosis when other parameters are considered. https://gorm.com.tr/index.php/GORM/article/view/1386Diabetes MellitusEndometrial NeoplasmsGlycated Hemoglobin A |
| spellingShingle | Ayse Rabia Senkaya Sercan Kantarci Suna Yildirim Karaca Muzaffer Sanci Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients Gynecology Obstetrics & Reproductive Medicine Diabetes Mellitus Endometrial Neoplasms Glycated Hemoglobin A |
| title | Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients |
| title_full | Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients |
| title_fullStr | Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients |
| title_full_unstemmed | Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients |
| title_short | Hemoglobin A1c Level is Associated with Lymphovascular Space Invasion in Diabetic Endometrial Cancer Patients |
| title_sort | hemoglobin a1c level is associated with lymphovascular space invasion in diabetic endometrial cancer patients |
| topic | Diabetes Mellitus Endometrial Neoplasms Glycated Hemoglobin A |
| url | https://gorm.com.tr/index.php/GORM/article/view/1386 |
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