A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature

Oral Squamous Cell Carcinoma (OSCC) shows an overall 5 yr survival rate of just above 50%. With an estimated 390,000 new cases per year the current therapeutic approaches have failed in the past 20 yr to improve survival. Reducing the burden of this malignancy represents a challenge for clinicians a...

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Main Authors: Guida Agostino, Perri Francesco, Annunziata Marco, Monteiro Luis, Warnakulasuriya Saman
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:Journal of Oral Medicine and Oral Surgery
Subjects:
Online Access:https://www.jomos.org/articles/mbcb/full_html/2025/01/mbcb250012/mbcb250012.html
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author Guida Agostino
Perri Francesco
Annunziata Marco
Monteiro Luis
Warnakulasuriya Saman
author_facet Guida Agostino
Perri Francesco
Annunziata Marco
Monteiro Luis
Warnakulasuriya Saman
author_sort Guida Agostino
collection DOAJ
description Oral Squamous Cell Carcinoma (OSCC) shows an overall 5 yr survival rate of just above 50%. With an estimated 390,000 new cases per year the current therapeutic approaches have failed in the past 20 yr to improve survival. Reducing the burden of this malignancy represents a challenge for clinicians around the globe. Early diagnosis represents the most effective option to reduce the impact of OSCC. Several chairside adjunctive techniques have been researched for the early diagnosis of OSCC but many of them have been found to have limited application due to their low sensitivity and specificity. Narrow Band Imaging (NBI) has the potential to be a useful aid for the clinician involved in the diagnosis and management of Oral Potentially Malignant Disorders (OPMDs) and OSCC. NBI fibroscopy is able to show microvasculature of oral lesions, possibly indicating the likelihood of malignant transformation. Yet, due to its high costs, the long learning curve, and the necessity for calibration of the users its application requires through careful investigation. We performed a review of the existing literature and, by showcasing some clinical cases, we aim to give the clinicians a practical guide to perform NBI when managing OPMD lesions of the different anatomical subsites of the oral cavity, based on the existing clinical evidence.
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issn 2608-1326
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spelling doaj-art-c3e67ee84ac841f790eb470f0f79d2122025-08-20T03:02:10ZengEDP SciencesJournal of Oral Medicine and Oral Surgery2608-13262025-01-01311310.1051/mbcb/2025005mbcb250012A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literatureGuida Agostino0https://orcid.org/0000-0003-0177-1301Perri Francesco1Annunziata Marco2Monteiro Luis3Warnakulasuriya Saman4U.O.C. Odontostomatologia A.O.R.N. A. CardarelliHead and Neck Medical Oncology Unit, Istituto Nazionale Tumori, IRCCSMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania “Luigi Vanvitelli”University Institute of Health Sciences (IUCS), Cooperativa de Ensino Superior Politécnico e Universitário (CESPU)King's College London & WHO Collaboration Centre for Oral CancerOral Squamous Cell Carcinoma (OSCC) shows an overall 5 yr survival rate of just above 50%. With an estimated 390,000 new cases per year the current therapeutic approaches have failed in the past 20 yr to improve survival. Reducing the burden of this malignancy represents a challenge for clinicians around the globe. Early diagnosis represents the most effective option to reduce the impact of OSCC. Several chairside adjunctive techniques have been researched for the early diagnosis of OSCC but many of them have been found to have limited application due to their low sensitivity and specificity. Narrow Band Imaging (NBI) has the potential to be a useful aid for the clinician involved in the diagnosis and management of Oral Potentially Malignant Disorders (OPMDs) and OSCC. NBI fibroscopy is able to show microvasculature of oral lesions, possibly indicating the likelihood of malignant transformation. Yet, due to its high costs, the long learning curve, and the necessity for calibration of the users its application requires through careful investigation. We performed a review of the existing literature and, by showcasing some clinical cases, we aim to give the clinicians a practical guide to perform NBI when managing OPMD lesions of the different anatomical subsites of the oral cavity, based on the existing clinical evidence.https://www.jomos.org/articles/mbcb/full_html/2025/01/mbcb250012/mbcb250012.htmloral squamous cell carcinomanarrow band imagingearly detection
spellingShingle Guida Agostino
Perri Francesco
Annunziata Marco
Monteiro Luis
Warnakulasuriya Saman
A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
Journal of Oral Medicine and Oral Surgery
oral squamous cell carcinoma
narrow band imaging
early detection
title A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
title_full A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
title_fullStr A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
title_full_unstemmed A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
title_short A practical guide to the use of Narrow Band Imaging (NBI) in the early detection of oral cancer: case series and review of the literature
title_sort practical guide to the use of narrow band imaging nbi in the early detection of oral cancer case series and review of the literature
topic oral squamous cell carcinoma
narrow band imaging
early detection
url https://www.jomos.org/articles/mbcb/full_html/2025/01/mbcb250012/mbcb250012.html
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