The Beneficial Roles of Seaweed in Atopic Dermatitis
Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by severe pruritus and recurrent flare-ups, significantly impacting patients’ quality of life. Current treatments, such as corticosteroids and immunomodulators, often provide symptomatic relief but can lead to adverse eff...
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MDPI AG
2024-12-01
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| Series: | Marine Drugs |
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| Online Access: | https://www.mdpi.com/1660-3397/22/12/566 |
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| author | Ah-Reum Kim Myeong-Jin Kim Jaeseong Seo Kyoung Mi Moon Bonggi Lee |
| author_facet | Ah-Reum Kim Myeong-Jin Kim Jaeseong Seo Kyoung Mi Moon Bonggi Lee |
| author_sort | Ah-Reum Kim |
| collection | DOAJ |
| description | Atopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by severe pruritus and recurrent flare-ups, significantly impacting patients’ quality of life. Current treatments, such as corticosteroids and immunomodulators, often provide symptomatic relief but can lead to adverse effects with prolonged use. Seaweed, a sustainable and nutrient-dense resource, has emerged as a promising alternative due to its rich bioactive compounds—polysaccharides, phlorotannins, polyphenols, and chlorophyll—that offer anti-inflammatory, antioxidant, and immunomodulatory properties. This review explores the therapeutic potential of brown, red, and green algae in alleviating AD symptoms, highlighting the effects of specific species, including <i>Undaria pinnatifida</i>, <i>Laminaria japonica</i>, <i>Chlorella vulgaris</i>, and <i>Sargassum horneri</i>. These seaweeds modulate immune responses, reduce epidermal thickness, and restore skin barrier function, presenting a novel, safe, and effective approach to AD management. Further clinical studies are needed to confirm their efficacy and establish dosing strategies, paving the way for seaweed-derived therapies as natural alternatives in AD treatment. |
| format | Article |
| id | doaj-art-c3e3fa1c98214d5c9cce6ee5625863a4 |
| institution | Kabale University |
| issn | 1660-3397 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
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| series | Marine Drugs |
| spelling | doaj-art-c3e3fa1c98214d5c9cce6ee5625863a42024-12-27T14:37:41ZengMDPI AGMarine Drugs1660-33972024-12-01221256610.3390/md22120566The Beneficial Roles of Seaweed in Atopic DermatitisAh-Reum Kim0Myeong-Jin Kim1Jaeseong Seo2Kyoung Mi Moon3Bonggi Lee4Department of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of KoreaKorean Medicine (KM)—Application Center, Korea Institute of Oriental Medicine, Daegu 41062, Republic of KoreaDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of KoreaDepartment of Food Science and Nutrition, Pukyong National University, Busan 48513, Republic of KoreaDepartment of Smart Green Technology Engineering, Pukyong National University, Busan 48513, Republic of KoreaAtopic dermatitis (AD) is a chronic, inflammatory skin condition characterized by severe pruritus and recurrent flare-ups, significantly impacting patients’ quality of life. Current treatments, such as corticosteroids and immunomodulators, often provide symptomatic relief but can lead to adverse effects with prolonged use. Seaweed, a sustainable and nutrient-dense resource, has emerged as a promising alternative due to its rich bioactive compounds—polysaccharides, phlorotannins, polyphenols, and chlorophyll—that offer anti-inflammatory, antioxidant, and immunomodulatory properties. This review explores the therapeutic potential of brown, red, and green algae in alleviating AD symptoms, highlighting the effects of specific species, including <i>Undaria pinnatifida</i>, <i>Laminaria japonica</i>, <i>Chlorella vulgaris</i>, and <i>Sargassum horneri</i>. These seaweeds modulate immune responses, reduce epidermal thickness, and restore skin barrier function, presenting a novel, safe, and effective approach to AD management. Further clinical studies are needed to confirm their efficacy and establish dosing strategies, paving the way for seaweed-derived therapies as natural alternatives in AD treatment.https://www.mdpi.com/1660-3397/22/12/566atopic dermatitisseaweedanti-inflammatoryimmunomodulationskin barrierseaweed-derived therapy |
| spellingShingle | Ah-Reum Kim Myeong-Jin Kim Jaeseong Seo Kyoung Mi Moon Bonggi Lee The Beneficial Roles of Seaweed in Atopic Dermatitis Marine Drugs atopic dermatitis seaweed anti-inflammatory immunomodulation skin barrier seaweed-derived therapy |
| title | The Beneficial Roles of Seaweed in Atopic Dermatitis |
| title_full | The Beneficial Roles of Seaweed in Atopic Dermatitis |
| title_fullStr | The Beneficial Roles of Seaweed in Atopic Dermatitis |
| title_full_unstemmed | The Beneficial Roles of Seaweed in Atopic Dermatitis |
| title_short | The Beneficial Roles of Seaweed in Atopic Dermatitis |
| title_sort | beneficial roles of seaweed in atopic dermatitis |
| topic | atopic dermatitis seaweed anti-inflammatory immunomodulation skin barrier seaweed-derived therapy |
| url | https://www.mdpi.com/1660-3397/22/12/566 |
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