Jawbone mesenchymal stromal cells attenuate acute inflammation via hematopoietic niche reinforcement

Jawbone mesenchymal stromal cells attenuate acute inflammation via hematopoietic niche reinforcement

BackgroundThe bone marrow microenvironment, comprising various cell types and molecular signals, finely orchestrates the self‐renewal and lineage commitment of hematopoietic stem cells (HSCs). Although most investigations have centered on mesenchymal stem cells (MSCs) from long bones, the distinct p...

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Main Authors: Xinyu Wang, Qianye Chen, Jiping Sun, Zihan Huang, Zijian Zhang, Tingwei Lu, Xiangru Huang, Siyuan Sun, Yuanqi Liu, Houwen Pan, Li Mei, Paul R. Cooper, Qinggang Dai, Lei Shen, Lingyong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
jawbone mesenchymal stem cells
hematopoietic stem cells
acute infection
exocrine
cell therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2025.1596143/full
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