Reawakening inflammation in the chronically injured spinal cord using lipopolysaccharide induces diverse microglial states

Reawakening inflammation in the chronically injured spinal cord using lipopolysaccharide induces diverse microglial states

Abstract Background Rehabilitative training is an effective method to promote recovery following spinal cord injury (SCI), with lower training efficacy observed in the chronic stage. The increased training efficacy during the subacute period is associated with a shift towards a more adaptive or pror...

Full description

Saved in:
Bibliographic Details
Main Authors: Rebecca K. John, Sadie P. Vogel, Sameera Zia, Kelly V. Lee, Antoinette T. Nguyen, Abel Torres-Espin, Keith K. Fenrich, Carmen Ng, Emma K. A. Schmidt, Romana Vavrek, Pamela J. F. Raposo, Keira Smith, Karim Fouad, Jason R. Plemel
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Neuroinflammation
Subjects:
Microglia
Spinal cord injury
Inflammation
Single-cell RNA sequencing
Plasticity
Lipopolysaccharide
Online Access:https://doi.org/10.1186/s12974-025-03379-6
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doi.org/10.1186/s12974-025-03379-6

Similar Items