Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy
The use of tumor necrosis factor-α (TNF-α) inhibitors in the treatment of various inflammatory conditions has altered the field of medical therapeutics. Squamous cell carcinoma is the second most common cancer of the skin, usually affecting sun-exposed areas of the body. We present here the case of...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/315490 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832552098424684544 |
|---|---|
| author | Efstathios Rallis Vasiliki-Kalliopi Bournia Constantinos Verros Alexios Iliopoulos |
| author_facet | Efstathios Rallis Vasiliki-Kalliopi Bournia Constantinos Verros Alexios Iliopoulos |
| author_sort | Efstathios Rallis |
| collection | DOAJ |
| description | The use of tumor necrosis factor-α (TNF-α) inhibitors in the treatment of various inflammatory conditions has altered the field of medical therapeutics. Squamous cell carcinoma is the second most common cancer of the skin, usually affecting sun-exposed areas of the body. We present here the case of a 75-year-old woman with rheumatoid arthritis, who developed an intertoe squamous cell carcinoma (SCC) of the right foot. According to her history, she received etanercept and methotrexate for 5 years for rheumatoid arthritis. The rare localization of this cancer could suggest a possible linkage of the malignancy to the chronic intake of anti-TNF-α treatment. This is the first reported case of an interdigital SCC developed under the use of an anti-TNF-α agent. |
| format | Article |
| id | doaj-art-c3d65081fbe641ecad0f5e1efaa16340 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-c3d65081fbe641ecad0f5e1efaa163402025-02-03T05:59:33ZengWileyCase Reports in Medicine1687-96271687-96352015-01-01201510.1155/2015/315490315490Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept TherapyEfstathios Rallis0Vasiliki-Kalliopi Bournia1Constantinos Verros2Alexios Iliopoulos3Department of Dermatology, Veterans Administration Hospital (NIMTS), Monis Petraki 10-12, 11521 Athens, GreeceDepartment of Rheumatology, Veterans Administration Hospital (NIMTS), Monis Petraki 10-12, 11521 Athens, GreecePrivate Practice, Tripolis, GreeceDepartment of Rheumatology, Veterans Administration Hospital (NIMTS), Monis Petraki 10-12, 11521 Athens, GreeceThe use of tumor necrosis factor-α (TNF-α) inhibitors in the treatment of various inflammatory conditions has altered the field of medical therapeutics. Squamous cell carcinoma is the second most common cancer of the skin, usually affecting sun-exposed areas of the body. We present here the case of a 75-year-old woman with rheumatoid arthritis, who developed an intertoe squamous cell carcinoma (SCC) of the right foot. According to her history, she received etanercept and methotrexate for 5 years for rheumatoid arthritis. The rare localization of this cancer could suggest a possible linkage of the malignancy to the chronic intake of anti-TNF-α treatment. This is the first reported case of an interdigital SCC developed under the use of an anti-TNF-α agent.http://dx.doi.org/10.1155/2015/315490 |
| spellingShingle | Efstathios Rallis Vasiliki-Kalliopi Bournia Constantinos Verros Alexios Iliopoulos Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy Case Reports in Medicine |
| title | Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy |
| title_full | Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy |
| title_fullStr | Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy |
| title_full_unstemmed | Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy |
| title_short | Intertoe Squamous Cell Carcinoma Developed in a Patient with Rheumatoid Arthritis under Etanercept Therapy |
| title_sort | intertoe squamous cell carcinoma developed in a patient with rheumatoid arthritis under etanercept therapy |
| url | http://dx.doi.org/10.1155/2015/315490 |
| work_keys_str_mv | AT efstathiosrallis intertoesquamouscellcarcinomadevelopedinapatientwithrheumatoidarthritisunderetanercepttherapy AT vasilikikalliopibournia intertoesquamouscellcarcinomadevelopedinapatientwithrheumatoidarthritisunderetanercepttherapy AT constantinosverros intertoesquamouscellcarcinomadevelopedinapatientwithrheumatoidarthritisunderetanercepttherapy AT alexiosiliopoulos intertoesquamouscellcarcinomadevelopedinapatientwithrheumatoidarthritisunderetanercepttherapy |