Variations in salivary microbiota and metabolic phenotype related to oral lichen planus with psychiatric symptoms

Variations in salivary microbiota and metabolic phenotype related to oral lichen planus with psychiatric symptoms

Abstract Background Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral mucosa with a certain tendency for malignant transformation. The etiology and pathogenesis of OLP remain unclear, and the relationship between psychiatric factors and the development of OLP has attracte...

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Main Authors: Kuichi Chen, Yuqi Qin, Li Yan, Yunmei Dong, Shiping Lv, Jingyi Xu, Ning Kang, Zhuoyan Luo, Yiyun Liu, Juncai Pu, Fangchun Chen, Xin Jin
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Oral Health
Subjects:
Oral lichen planus
Psychiatric symptoms
Oral microbiota
Metabolomics
16S rRNA gene sequencing
LC-MS
Online Access:https://doi.org/10.1186/s12903-025-06439-8
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