WGCNA combined with machine learning for analysis of diagnostic markers of preeclampsia associated with the hedgehog signaling pathway

WGCNA combined with machine learning for analysis of diagnostic markers of preeclampsia associated with the hedgehog signaling pathway

Background Abnormal hedgehog (Hh) signaling is linked to preeclampsia (PE). This study aimed to identify Hh-related diagnostic biomarkers for PE and assess the role of immune infiltration.Methods The PE dataset was obtained from GEO to screen DEGs. WGCNA was utilized to identify Hh pathway-related g...

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Bibliographic Details
Main Authors: Xiaofeng Wang, Yichi Xu, Junpeng Dong, Jinwen Zhang, Wei Gu, Xiaoli Qin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Hypertension in Pregnancy
Subjects:
Preeclampsia
hedgehog signaling pathway
WGCNA
machine learning
diagnostic marker
Online Access:https://www.tandfonline.com/doi/10.1080/10641955.2025.2542869
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