Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults

Background: Assessing quality of life (QOL) in individuals with Alzheimer's disease (AD) is particularly challenging due to the subjective nature of the concept and the cognitive deficits associated with the condition. This study aimed to translate the AD-Related QOL (ADRQL) questionnaire into...

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Main Authors: Masoud Gharib, Jafar Hajghani, Hamed Cheraghmakani, Vahid Rashedi
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Aging and Health Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667032125000101
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author Masoud Gharib
Jafar Hajghani
Hamed Cheraghmakani
Vahid Rashedi
author_facet Masoud Gharib
Jafar Hajghani
Hamed Cheraghmakani
Vahid Rashedi
author_sort Masoud Gharib
collection DOAJ
description Background: Assessing quality of life (QOL) in individuals with Alzheimer's disease (AD) is particularly challenging due to the subjective nature of the concept and the cognitive deficits associated with the condition. This study aimed to translate the AD-Related QOL (ADRQL) questionnaire into Persian and rigorously evaluate its reliability and validity in this population. Methods: This cross-sectional methodological study was conducted between March 2021 and August 2022, involving 220 patients diagnosed with AD according to DSM-IV criteria, along with their primary caregivers. The Persian version of the ADRQL (P-ADRQL) and the QOL in Late-Stage Dementia (QUALID) scales were used to collect data, allowing for a thorough assessment of QOL across multiple domains. Results: The P-ADRQL demonstrated excellent psychometric properties, with an overall Cronbach's alpha of 0.92, indicating strong internal consistency. This suggests that the items reliably measure the construct of QOL in patients with AD. Additionally, test-retest analysis revealed consistent scores across all subscales, confirming the stability of caregiver assessments over time. Significant correlations between P-ADRQL and QUALID further supported the convergent validity of the instrument, affirming its ability to measure QOL in alignment with established dementia assessment tools. Conclusion: The P-ADRQL is a robust and reliable instrument for evaluating QOL in older Iranian adults with AD. Its strong psychometric properties ensure accurate and consistent assessments, addressing a critical need within Iran's healthcare system.
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spelling doaj-art-c3c766226c0a40ff9cb2c6013eea64482025-08-20T03:24:36ZengElsevierAging and Health Research2667-03212025-06-015210022910.1016/j.ahr.2025.100229Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adultsMasoud Gharib0Jafar Hajghani1Hamed Cheraghmakani2Vahid Rashedi3Orthopedic Research Center, Department of Rehabilitation, Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, IranOrthopedic Research Center, Department of Rehabilitation, Faculty of Paramedical Sciences, Mazandaran University of Medical Sciences, Sari, IranDepartment of Neurology, Bou Ali Sina Hospital, Mazandaran University of Medical Sciences, Sari, IranIranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran; Corresponding author at: Iranian Research Center on Aging, Department of Aging, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran.Background: Assessing quality of life (QOL) in individuals with Alzheimer's disease (AD) is particularly challenging due to the subjective nature of the concept and the cognitive deficits associated with the condition. This study aimed to translate the AD-Related QOL (ADRQL) questionnaire into Persian and rigorously evaluate its reliability and validity in this population. Methods: This cross-sectional methodological study was conducted between March 2021 and August 2022, involving 220 patients diagnosed with AD according to DSM-IV criteria, along with their primary caregivers. The Persian version of the ADRQL (P-ADRQL) and the QOL in Late-Stage Dementia (QUALID) scales were used to collect data, allowing for a thorough assessment of QOL across multiple domains. Results: The P-ADRQL demonstrated excellent psychometric properties, with an overall Cronbach's alpha of 0.92, indicating strong internal consistency. This suggests that the items reliably measure the construct of QOL in patients with AD. Additionally, test-retest analysis revealed consistent scores across all subscales, confirming the stability of caregiver assessments over time. Significant correlations between P-ADRQL and QUALID further supported the convergent validity of the instrument, affirming its ability to measure QOL in alignment with established dementia assessment tools. Conclusion: The P-ADRQL is a robust and reliable instrument for evaluating QOL in older Iranian adults with AD. Its strong psychometric properties ensure accurate and consistent assessments, addressing a critical need within Iran's healthcare system.http://www.sciencedirect.com/science/article/pii/S2667032125000101Alzheimer's diseaseDementiaQuality of lifeOlder adultsPsychometrics
spellingShingle Masoud Gharib
Jafar Hajghani
Hamed Cheraghmakani
Vahid Rashedi
Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
Aging and Health Research
Alzheimer's disease
Dementia
Quality of life
Older adults
Psychometrics
title Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
title_full Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
title_fullStr Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
title_full_unstemmed Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
title_short Validity and reliability of the Persian version of Alzheimer's disease-related quality of life (P-ADRQL) questionnaire among older Iranian adults
title_sort validity and reliability of the persian version of alzheimer s disease related quality of life p adrql questionnaire among older iranian adults
topic Alzheimer's disease
Dementia
Quality of life
Older adults
Psychometrics
url http://www.sciencedirect.com/science/article/pii/S2667032125000101
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