THBS1 mediates hypoxia driven EndMT in pulmonary hypertension

THBS1 mediates hypoxia driven EndMT in pulmonary hypertension

Abstract Long‐term hypoxia is one of the main causes of pulmonary vascular remodeling in pulmonary hypertension (PH) associated with congenital heart disease (CHD) children. Endothelial to mesenchymal transition (EndMT) is an important pathological basis of pulmonary vascular remodeling in PH. We ob...

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Bibliographic Details
Main Authors: Bingming Peng, Yingzhen Zhou, Xingmeng Fu, Li Chen, Zhengxia Pan, Qijian Yi, Tengteng Zhao, Zhou Fu, Ting Wang
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:Pulmonary Circulation
Subjects:
EndMT
hypoxia
pulmonary hypertension
pulmonary vascular remodeling
THBS1
Online Access:https://doi.org/10.1002/pul2.70019
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