Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report
We report a rare presentation of limbus-sparing ocular surface squamous neoplasia (OSSN) over post-traumatic adherent leucoma. A 32-year-old healthy male presented with a pedunculated fleshy corneal mass overlying an adherent leucoma secondary to self-healed full-thickness corneal laceration, with a...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2024-12-01
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| Series: | TNOA Journal of Ophthalmic Science and Research |
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| Online Access: | https://journals.lww.com/10.4103/tjosr.tjosr_114_24 |
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| author | Keerti Wali Nikita Sankolli Savitri Nerune |
| author_facet | Keerti Wali Nikita Sankolli Savitri Nerune |
| author_sort | Keerti Wali |
| collection | DOAJ |
| description | We report a rare presentation of limbus-sparing ocular surface squamous neoplasia (OSSN) over post-traumatic adherent leucoma. A 32-year-old healthy male presented with a pedunculated fleshy corneal mass overlying an adherent leucoma secondary to self-healed full-thickness corneal laceration, with an adjacent pinguecula separated by a clear normal limbus. AS-OCT confirmed the separation of corneal epithelial mass from underlying iris tissue by thinned scarred corneal stroma. An excisional biopsy with 2mm conjunctival margins and a limbal conjunctival autograft was performed. A feeder vessel was observed at the base of the corneal lesion. Histopathological evaluation showed moderately differentiated squamous cell carcinoma. Adjuvant Interferon alfa 2b chemotherapy for three months ensured complete clearance with no recurrence at follow-up. This case highlights the traumatic etiology of OSSN development without limbal involvement. Immediate corneal tear repair may have prevented its occurrence and the need for long-term chemotherapy. |
| format | Article |
| id | doaj-art-c3c5c3bf995d4b1a92ddfe84ca76477a |
| institution | DOAJ |
| issn | 2589-4528 2589-4536 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | TNOA Journal of Ophthalmic Science and Research |
| spelling | doaj-art-c3c5c3bf995d4b1a92ddfe84ca76477a2025-08-20T02:41:20ZengWolters Kluwer Medknow PublicationsTNOA Journal of Ophthalmic Science and Research2589-45282589-45362024-12-0162448248410.4103/tjosr.tjosr_114_24Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case ReportKeerti WaliNikita SankolliSavitri NeruneWe report a rare presentation of limbus-sparing ocular surface squamous neoplasia (OSSN) over post-traumatic adherent leucoma. A 32-year-old healthy male presented with a pedunculated fleshy corneal mass overlying an adherent leucoma secondary to self-healed full-thickness corneal laceration, with an adjacent pinguecula separated by a clear normal limbus. AS-OCT confirmed the separation of corneal epithelial mass from underlying iris tissue by thinned scarred corneal stroma. An excisional biopsy with 2mm conjunctival margins and a limbal conjunctival autograft was performed. A feeder vessel was observed at the base of the corneal lesion. Histopathological evaluation showed moderately differentiated squamous cell carcinoma. Adjuvant Interferon alfa 2b chemotherapy for three months ensured complete clearance with no recurrence at follow-up. This case highlights the traumatic etiology of OSSN development without limbal involvement. Immediate corneal tear repair may have prevented its occurrence and the need for long-term chemotherapy.https://journals.lww.com/10.4103/tjosr.tjosr_114_24adherent leucomaanterior segment optical coherence tomographycorneal tearinterferon alfa 2bocular surface squamous neoplasia |
| spellingShingle | Keerti Wali Nikita Sankolli Savitri Nerune Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report TNOA Journal of Ophthalmic Science and Research adherent leucoma anterior segment optical coherence tomography corneal tear interferon alfa 2b ocular surface squamous neoplasia |
| title | Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report |
| title_full | Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report |
| title_fullStr | Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report |
| title_full_unstemmed | Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report |
| title_short | Post-traumatic Corneal Ocular Surface Squamous Neoplasia: A Case Report |
| title_sort | post traumatic corneal ocular surface squamous neoplasia a case report |
| topic | adherent leucoma anterior segment optical coherence tomography corneal tear interferon alfa 2b ocular surface squamous neoplasia |
| url | https://journals.lww.com/10.4103/tjosr.tjosr_114_24 |
| work_keys_str_mv | AT keertiwali posttraumaticcornealocularsurfacesquamousneoplasiaacasereport AT nikitasankolli posttraumaticcornealocularsurfacesquamousneoplasiaacasereport AT savitrinerune posttraumaticcornealocularsurfacesquamousneoplasiaacasereport |