Bicyclic peptide-enhanced covalent inhibitor of SARS-CoV-2 3CL protease
Aim: Develop technology to apply bicyclic peptides for discovering covalent inhibitors of proteases and use this technology to create bicyclic peptide—warhead conjugates for targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 3C-like (3CL) protease. Enhance the potency of the...
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Main Authors: | Qian Wang, Yanhui Wang, Jian Li, Hong Liu, Shiyu Chen |
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Format: | Article |
Language: | English |
Published: |
Open Exploration
2024-10-01
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Series: | Exploration of Drug Science |
Subjects: | |
Online Access: | https://www.explorationpub.com/uploads/Article/A100871/100871.pdf |
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