Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis

Saved in:
Bibliographic Details
Main Author: Bi-Sen Ding
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525003594
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849424763326300160
author Bi-Sen Ding
author_facet Bi-Sen Ding
author_sort Bi-Sen Ding
collection DOAJ
format Article
id doaj-art-c3c29e1dc3334018b281cb0ad8a3a048
institution Kabale University
issn 2211-3835
language English
publishDate 2025-06-01
publisher Elsevier
record_format Article
series Acta Pharmaceutica Sinica B
spelling doaj-art-c3c29e1dc3334018b281cb0ad8a3a0482025-08-20T03:30:02ZengElsevierActa Pharmaceutica Sinica B2211-38352025-06-011563351335210.1016/j.apsb.2025.05.028Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axisBi-Sen Ding0Corresponding author.; Key Lab of Birth Defects and Related Diseases of Women and Children of MOE, State Key Lab of Biotherapy, State Key Laboratory of Respiratory Health and Multimorbidity, West China Second University Hospital, College of Life Sciences, Sichuan University, Chengdu 610064, Chinahttp://www.sciencedirect.com/science/article/pii/S2211383525003594Lung fibrosisAlternative splicingSRSF7PKM exon skippingFibroblast activationLomitapide
spellingShingle Bi-Sen Ding
Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
Acta Pharmaceutica Sinica B
Lung fibrosis
Alternative splicing
SRSF7
PKM exon skipping
Fibroblast activation
Lomitapide
title Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
title_full Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
title_fullStr Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
title_full_unstemmed Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
title_short Unlocking the therapeutic potential of RNA splicing in lung fibrosis: Insights from the SRSF7–PKM axis
title_sort unlocking the therapeutic potential of rna splicing in lung fibrosis insights from the srsf7 pkm axis
topic Lung fibrosis
Alternative splicing
SRSF7
PKM exon skipping
Fibroblast activation
Lomitapide
url http://www.sciencedirect.com/science/article/pii/S2211383525003594
work_keys_str_mv AT bisending unlockingthetherapeuticpotentialofrnasplicinginlungfibrosisinsightsfromthesrsf7pkmaxis