High-throughput LDI MS technology decodes the distinct metabolic landscape of prostate cancer in a large-scale cohort

High-throughput LDI MS technology decodes the distinct metabolic landscape of prostate cancer in a large-scale cohort

Abstract Background Prostate cancer (PCa) remains a leading global malignancy, yet current diagnostic reliance on prostate-specific antigen (PSA) testing is limited by suboptimal sensitivity and specificity for early-stage detection. The present study aims to establish an effective high-throughput s...

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Main Authors:	Xinrong Jiang, Chen Zhang, Jing Le, Jie Zhang, Shuo Cao, Xinran Xu, Xiaoming Chen, Sheng Cheng, Haitao Yu, Haofei Jiang, Ruichen Zang, Kunyu Wang, Weiwu Chen, Haobo Fan, Jianmin Wu, Yanlan Yu, Guoqing Ding
Format:	Article
Language:	English
Published:	BMC 2025-07-01
Series:	Biomarker Research
Subjects:	Metabolomics Prostate cancer Benign prostatic hyperplasia Non-invasive diagnosis Laser desorption/Ionization mass spectrometry
Online Access:	https://doi.org/10.1186/s40364-025-00804-z
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