Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study
Background: Hemodynamic parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and oxygen saturation (SpO2) are critical in evaluating cardiovascular stability during surgical procedures. Anxiety, a common psychological condition, has been linked to hemody...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-06-01
|
| Series: | Journal of Pharmacy and Bioallied Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jpbs.jpbs_476_25 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849420965809750016 |
|---|---|
| author | E. S. Shobha M. D Anagha Vinod Rangan Yashas N. Raj Meghana Patil B. K. Ramnarayan |
| author_facet | E. S. Shobha M. D Anagha Vinod Rangan Yashas N. Raj Meghana Patil B. K. Ramnarayan |
| author_sort | E. S. Shobha |
| collection | DOAJ |
| description | Background:
Hemodynamic parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and oxygen saturation (SpO2) are critical in evaluating cardiovascular stability during surgical procedures. Anxiety, a common psychological condition, has been linked to hemodynamic fluctuations, particularly in hypertensive patients.
Materials and Methods:
This observational study included 27 hypertensive patients scheduled for impacted third molar extraction under local anesthesia. Anxiety levels were assessed preoperatively using the Amsterdam Preoperative Anxiety and Information Scale (APAIS). Hemodynamic parameters (SBP, DBP, HR, and SpO2) were measured preoperatively, intraoperatively, and postoperatively using a sphygmomanometer and pulse oximeter. Statistical analysis was conducted using the Wilcoxon signed rank test and Mann–Whitney test, with a significance threshold of P < 0.05.
Results:
A significant increase in HR was observed from preoperative (74.07 ± 3.78 bpm) to intraoperative (76.78 ± 6.08 bpm, P = 0.005), and from preoperative to postoperative (94.70 ± 3.75 bpm, P < 0.001). SpO2 levels significantly decreased from preoperative (94.89 ± 4.40%) to postoperative (75.70 ± 5.68%, P < 0.001). Although SBP increased intraoperatively (129.26 ± 7.21 mmHg) compared to preoperative levels (127.52 ± 10.08 mmHg), the difference was not statistically significant (P > 0.05). However, a significant decline in SBP was noted postoperatively (126.52 ± 7.91 mmHg, P = 0.006). No significant variations in DBP were recorded across time points (P > 0.05). Gender-based comparisons revealed no significant differences in anxiety scores (P > 0.05), except for postoperative HR, which was significantly higher in females (95.61 ± 2.99 bpm) compared to males (92.89 ± 4.59 bpm, P = 0.043).
Conclusion:
Anxiety significantly impacts HR and SpO2 levels in hypertensive patients undergoing impacted third molar extraction. Although SBP changes were significant postoperatively, DBP remained stable across time points. |
| format | Article |
| id | doaj-art-c3bc5e7dbe274cca9f6a628f57e6b87e |
| institution | Kabale University |
| issn | 0976-4879 0975-7406 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Pharmacy and Bioallied Sciences |
| spelling | doaj-art-c3bc5e7dbe274cca9f6a628f57e6b87e2025-08-20T03:31:35ZengWolters Kluwer Medknow PublicationsJournal of Pharmacy and Bioallied Sciences0976-48790975-74062025-06-0117Suppl 2S1817S181910.4103/jpbs.jpbs_476_25Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational StudyE. S. ShobhaM. D AnaghaVinod RanganYashas N. RajMeghana PatilB. K. RamnarayanBackground: Hemodynamic parameters such as systolic blood pressure (SBP), diastolic blood pressure (DBP), heart rate (HR), and oxygen saturation (SpO2) are critical in evaluating cardiovascular stability during surgical procedures. Anxiety, a common psychological condition, has been linked to hemodynamic fluctuations, particularly in hypertensive patients. Materials and Methods: This observational study included 27 hypertensive patients scheduled for impacted third molar extraction under local anesthesia. Anxiety levels were assessed preoperatively using the Amsterdam Preoperative Anxiety and Information Scale (APAIS). Hemodynamic parameters (SBP, DBP, HR, and SpO2) were measured preoperatively, intraoperatively, and postoperatively using a sphygmomanometer and pulse oximeter. Statistical analysis was conducted using the Wilcoxon signed rank test and Mann–Whitney test, with a significance threshold of P < 0.05. Results: A significant increase in HR was observed from preoperative (74.07 ± 3.78 bpm) to intraoperative (76.78 ± 6.08 bpm, P = 0.005), and from preoperative to postoperative (94.70 ± 3.75 bpm, P < 0.001). SpO2 levels significantly decreased from preoperative (94.89 ± 4.40%) to postoperative (75.70 ± 5.68%, P < 0.001). Although SBP increased intraoperatively (129.26 ± 7.21 mmHg) compared to preoperative levels (127.52 ± 10.08 mmHg), the difference was not statistically significant (P > 0.05). However, a significant decline in SBP was noted postoperatively (126.52 ± 7.91 mmHg, P = 0.006). No significant variations in DBP were recorded across time points (P > 0.05). Gender-based comparisons revealed no significant differences in anxiety scores (P > 0.05), except for postoperative HR, which was significantly higher in females (95.61 ± 2.99 bpm) compared to males (92.89 ± 4.59 bpm, P = 0.043). Conclusion: Anxiety significantly impacts HR and SpO2 levels in hypertensive patients undergoing impacted third molar extraction. Although SBP changes were significant postoperatively, DBP remained stable across time points.https://journals.lww.com/10.4103/jpbs.jpbs_476_25anxietyhemodynamic responseshypertensionimpacted mandibular third molarsurgical extraction |
| spellingShingle | E. S. Shobha M. D Anagha Vinod Rangan Yashas N. Raj Meghana Patil B. K. Ramnarayan Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study Journal of Pharmacy and Bioallied Sciences anxiety hemodynamic responses hypertension impacted mandibular third molar surgical extraction |
| title | Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study |
| title_full | Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study |
| title_fullStr | Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study |
| title_full_unstemmed | Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study |
| title_short | Evaluation of Anxiety-Induced Hemodynamics Response in Known Hypertensive Patients Undergoing Surgical Removal of Impacted Mandibular Third Molar Surgery: An Observational Study |
| title_sort | evaluation of anxiety induced hemodynamics response in known hypertensive patients undergoing surgical removal of impacted mandibular third molar surgery an observational study |
| topic | anxiety hemodynamic responses hypertension impacted mandibular third molar surgical extraction |
| url | https://journals.lww.com/10.4103/jpbs.jpbs_476_25 |
| work_keys_str_mv | AT esshobha evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy AT mdanagha evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy AT vinodrangan evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy AT yashasnraj evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy AT meghanapatil evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy AT bkramnarayan evaluationofanxietyinducedhemodynamicsresponseinknownhypertensivepatientsundergoingsurgicalremovalofimpactedmandibularthirdmolarsurgeryanobservationalstudy |