T cell immunophenotypes and IgE responses in patients with moderate‐to‐severe atopic dermatitis receiving dupilumab

T cell immunophenotypes and IgE responses in patients with moderate‐to‐severe atopic dermatitis receiving dupilumab

Abstract Background Targeting the interleukin‐4 receptor alpha (IL‐4Rα) subunit has proven clinical efficacy in atopic dermatitis (AD). Objective This study assessed the peripheral phenotype and function of T‐cells, but also levels of total and sIgE and its receptors in AD patients receiving dupilum...

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Bibliographic Details
Main Authors: Davender Redhu, Wojciech Francuzik, Philipp Globig, Margitta Worm
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Clinical and Translational Allergy
Subjects:
atopic dermatitis
dupilumab
IgE
immune modulation
T cell phenotyping
Online Access:https://doi.org/10.1002/clt2.70062
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