The neural correlates of visuospatial perceptual and oculomotor extrapolation.

The human visual system must perform complex visuospatial extrapolations (VSE) across space and time in order to extract shape and form from the retinal projection of a cluttered visual environment characterized by occluded surfaces and moving objects. Even if we exclude the temporal dimension, for...

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Main Authors: Marc Tibber, Ayse Pinar Saygin, Simon Grant, Dean Melmoth, Geraint Rees, Michael Morgan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009664&type=printable
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author Marc Tibber
Ayse Pinar Saygin
Simon Grant
Dean Melmoth
Geraint Rees
Michael Morgan
author_facet Marc Tibber
Ayse Pinar Saygin
Simon Grant
Dean Melmoth
Geraint Rees
Michael Morgan
author_sort Marc Tibber
collection DOAJ
description The human visual system must perform complex visuospatial extrapolations (VSE) across space and time in order to extract shape and form from the retinal projection of a cluttered visual environment characterized by occluded surfaces and moving objects. Even if we exclude the temporal dimension, for instance when judging whether an extended finger is pointing towards one object or another, the mechanisms of VSE remain opaque. Here we investigated the neural correlates of VSE using functional magnetic resonance imaging in sixteen human observers while they judged the relative position of, or saccaded to, a (virtual) target defined by the extrapolated path of a pointer. Using whole brain and region of interest (ROI) analyses, we compared the brain activity evoked by these VSE tasks to similar control judgements or eye movements made to explicit (dot) targets that did not require extrapolation. The data show that activity in an occipitotemporal region that included the lateral occipital cortex (LOC) was significantly greater during VSE than during control tasks. A similar, though less pronounced, pattern was also evident in regions of the fronto-parietal cortex that included the frontal eye fields. However, none of the ROIs examined exhibited a significant interaction between target type (extrapolated/explicit) and response type (oculomotor/perceptual). These findings are consistent with a close association between visuoperceptual and oculomotor responses, and highlight a critical role for the LOC in the process of VSE.
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spelling doaj-art-c3afbf22389e49b8838a66b3cfa0b72e2025-08-20T03:19:52ZengPublic Library of Science (PLoS)PLoS ONE1932-62032010-03-0153e966410.1371/journal.pone.0009664The neural correlates of visuospatial perceptual and oculomotor extrapolation.Marc TibberAyse Pinar SayginSimon GrantDean MelmothGeraint ReesMichael MorganThe human visual system must perform complex visuospatial extrapolations (VSE) across space and time in order to extract shape and form from the retinal projection of a cluttered visual environment characterized by occluded surfaces and moving objects. Even if we exclude the temporal dimension, for instance when judging whether an extended finger is pointing towards one object or another, the mechanisms of VSE remain opaque. Here we investigated the neural correlates of VSE using functional magnetic resonance imaging in sixteen human observers while they judged the relative position of, or saccaded to, a (virtual) target defined by the extrapolated path of a pointer. Using whole brain and region of interest (ROI) analyses, we compared the brain activity evoked by these VSE tasks to similar control judgements or eye movements made to explicit (dot) targets that did not require extrapolation. The data show that activity in an occipitotemporal region that included the lateral occipital cortex (LOC) was significantly greater during VSE than during control tasks. A similar, though less pronounced, pattern was also evident in regions of the fronto-parietal cortex that included the frontal eye fields. However, none of the ROIs examined exhibited a significant interaction between target type (extrapolated/explicit) and response type (oculomotor/perceptual). These findings are consistent with a close association between visuoperceptual and oculomotor responses, and highlight a critical role for the LOC in the process of VSE.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009664&type=printable
spellingShingle Marc Tibber
Ayse Pinar Saygin
Simon Grant
Dean Melmoth
Geraint Rees
Michael Morgan
The neural correlates of visuospatial perceptual and oculomotor extrapolation.
PLoS ONE
title The neural correlates of visuospatial perceptual and oculomotor extrapolation.
title_full The neural correlates of visuospatial perceptual and oculomotor extrapolation.
title_fullStr The neural correlates of visuospatial perceptual and oculomotor extrapolation.
title_full_unstemmed The neural correlates of visuospatial perceptual and oculomotor extrapolation.
title_short The neural correlates of visuospatial perceptual and oculomotor extrapolation.
title_sort neural correlates of visuospatial perceptual and oculomotor extrapolation
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0009664&type=printable
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