RBM14 enhances transcriptional activity of p23 regulating CXCL1 expression to induce lung cancer metastasis

RBM14 enhances transcriptional activity of p23 regulating CXCL1 expression to induce lung cancer metastasis

Metastasis serves as an indicator of malignancy and is a biological characteristic of carcinomas. Epithelial–mesenchymal transition (EMT) plays a key role in the promotion of tumor invasion and metastasis and in the enhancement of tumor cell aggressiveness. Prostaglandin E synthase 3 (p23) is a coch...

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Bibliographic Details
Main Authors: Wen Zhang, Yulin Peng, Meirong Zhou, Lei Qian, Yilin Che, Junlin Chen, Wenhao Zhang, Chengjian He, Minghang Qi, Xiaohong Shu, Manman Tian, Xiangge Tian, Yan Tian, Sa Deng, Yan Wang, Xiaokui Huo, Zhenlong Yu, Xiaochi Ma
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Lung cancer
Epithelial–mesenchymal transition
Invasion and metastasis
RNA-binding motif protein 14
Prostaglandin E synthase 3
CXCL1
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383525002163
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