The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation

Agave species represent an exceptional model of genetic diversity, climate resilience, and bioeconomic potential. The common ancestor of all mezcals, called “vino mezcal”, emerged in Colima and Jalisco in the 16th century, and from it came famous mezcals such as raicilla, tequila, bacanor...

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Main Author: Dolores Javier Sánchez González
Format: Article
Language:English
Published: Academia.edu Journals 2025-05-01
Series:Academia Molecular Biology and Genomics
Online Access:https://www.academia.edu/129607278/The_Agave_genus_in_the_genomics_era_evolution_biodiversity_and_sustainable_innovation
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author Dolores Javier Sánchez González
author_facet Dolores Javier Sánchez González
author_sort Dolores Javier Sánchez González
collection DOAJ
description Agave species represent an exceptional model of genetic diversity, climate resilience, and bioeconomic potential. The common ancestor of all mezcals, called “vino mezcal”, emerged in Colima and Jalisco in the 16th century, and from it came famous mezcals such as raicilla, tequila, bacanora, tuxca, and mezcal. Characterized by a unique bimodal karyotype and large nuclear genomes, Agave exhibits complex patterns of polyploidization, chromosomal rearrangements, and repetitive DNA accumulation that underpin its adaptation to arid environments. Advances in genomic research have revealed critical insights into its structure, emphasizing the urgent need for genetic conservation amid pressures from clonal propagation and industrial monoculture. The integration of high-throughput sequencing, cytogenetic mapping, and comparative genomics has opened new avenues for sustainable agriculture and biotechnological innovation, including biofuel production, bioplastics, and pharmaceutical applications. Nevertheless, maintaining biodiversity through the conservation of wild populations and the promotion of traditional agricultural practices remains critical for safeguarding the genus’s evolutionary potential. This review consolidates the latest findings in chromosome biology, genome architecture, and biotechnological applications of Agave, positioning it as a key species for green innovation in the face of global climate change. By bridging ecological heritage with modern genomic tools, Agave emerges not only as a crucial resource for economic development but also as a model of sustainable adaptation strategies for future agricultural systems.
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spelling doaj-art-c39c5d047dfa4ed19a3ba213d9292a342025-08-20T03:25:22ZengAcademia.edu JournalsAcademia Molecular Biology and Genomics3064-97652025-05-012210.20935/AcadMolBioGen7716The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovationDolores Javier Sánchez González0Postgraduate and Research Section, Higher School of Medicine, National Polytechnic Institute, Mexico City 11340, Mexico. Agave species represent an exceptional model of genetic diversity, climate resilience, and bioeconomic potential. The common ancestor of all mezcals, called “vino mezcal”, emerged in Colima and Jalisco in the 16th century, and from it came famous mezcals such as raicilla, tequila, bacanora, tuxca, and mezcal. Characterized by a unique bimodal karyotype and large nuclear genomes, Agave exhibits complex patterns of polyploidization, chromosomal rearrangements, and repetitive DNA accumulation that underpin its adaptation to arid environments. Advances in genomic research have revealed critical insights into its structure, emphasizing the urgent need for genetic conservation amid pressures from clonal propagation and industrial monoculture. The integration of high-throughput sequencing, cytogenetic mapping, and comparative genomics has opened new avenues for sustainable agriculture and biotechnological innovation, including biofuel production, bioplastics, and pharmaceutical applications. Nevertheless, maintaining biodiversity through the conservation of wild populations and the promotion of traditional agricultural practices remains critical for safeguarding the genus’s evolutionary potential. This review consolidates the latest findings in chromosome biology, genome architecture, and biotechnological applications of Agave, positioning it as a key species for green innovation in the face of global climate change. By bridging ecological heritage with modern genomic tools, Agave emerges not only as a crucial resource for economic development but also as a model of sustainable adaptation strategies for future agricultural systems.https://www.academia.edu/129607278/The_Agave_genus_in_the_genomics_era_evolution_biodiversity_and_sustainable_innovation
spellingShingle Dolores Javier Sánchez González
The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
Academia Molecular Biology and Genomics
title The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
title_full The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
title_fullStr The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
title_full_unstemmed The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
title_short The Agave genus in the genomics era: evolution, biodiversity, and sustainable innovation
title_sort agave genus in the genomics era evolution biodiversity and sustainable innovation
url https://www.academia.edu/129607278/The_Agave_genus_in_the_genomics_era_evolution_biodiversity_and_sustainable_innovation
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