Oral squamous cell carcinoma and associated risk factors: A case-control study

Introduction: Squamous cell carcinoma is the most frequent neoplasm of the head and neck. An adequate knowledge about its risk factors could reduce its morbidity and mortality. Objective: To identify the causal association between some risk factors and the apparition of the oral squamous cell carcin...

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Main Authors: Ibraín Enrique Corrales-Reyes, Vanesa Cruz-Sánchez, Christian R. Mejia
Format: Article
Language:Spanish
Published: Editorial Ciencias Médicas - ECIMED 2021-08-01
Series:Revista Cubana de Medicina Militar
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Online Access:http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1401
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author Ibraín Enrique Corrales-Reyes
Vanesa Cruz-Sánchez
Christian R. Mejia
author_facet Ibraín Enrique Corrales-Reyes
Vanesa Cruz-Sánchez
Christian R. Mejia
author_sort Ibraín Enrique Corrales-Reyes
collection DOAJ
description Introduction: Squamous cell carcinoma is the most frequent neoplasm of the head and neck. An adequate knowledge about its risk factors could reduce its morbidity and mortality. Objective: To identify the causal association between some risk factors and the apparition of the oral squamous cell carcinoma. Methods: Observational, analytic and case-control study conducted with patients treated at Carlos Manuel de Céspedes Provincial General Hospital's maxillofacial surgery service between January 1, 2018 and December 31, 2020. For the statistical analysis of the risk factors, the strength of the association with the Odds Ratio and its confidence intervals (95 % CI) was measured and later a multivariate analysis was performed. Results: The sample was comprised of 87 patients (29 cases and 58 controls). The 68.96% of the cases (n=20) were male patients and their average age was 63.03 years. People with history of alcohol consumption showed a 16 times greater risk (OR=16.03). Poor oral hygiene (OR: 5.23; CI 95%: 1.18-23.29; p=0.030) and traumatic irritants (OR: 4.41; CI 95 %: 1.01-19.23; p=0.048) were risk factors too. Conclusion: A strong association between the disease and the antecedent of alcohol consumption, the exposition to traumatic irritating and the poor oral hygiene was identified.
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spelling doaj-art-c39b6c57adf04dcf83f587b45850507a2025-08-20T02:15:41ZspaEditorial Ciencias Médicas - ECIMEDRevista Cubana de Medicina Militar1561-30462021-08-01503e02101401e02101401455Oral squamous cell carcinoma and associated risk factors: A case-control studyIbraín Enrique Corrales-Reyes0Vanesa Cruz-Sánchez1Christian R. Mejia2Universidad de Ciencias Médicas de Granma. Hospital General Universitario Carlos Manuel de Céspedes. Servicio de Cirugía MaxilofacialUniversidad de Ciencias Médicas de Granma. Hospital General Universitario Carlos Manuel de Céspedes. Servicio de Cirugía MaxilofacialUniversidad Norbert Wiener. Centro de Investigación en Medicina TraslacionalIntroduction: Squamous cell carcinoma is the most frequent neoplasm of the head and neck. An adequate knowledge about its risk factors could reduce its morbidity and mortality. Objective: To identify the causal association between some risk factors and the apparition of the oral squamous cell carcinoma. Methods: Observational, analytic and case-control study conducted with patients treated at Carlos Manuel de Céspedes Provincial General Hospital's maxillofacial surgery service between January 1, 2018 and December 31, 2020. For the statistical analysis of the risk factors, the strength of the association with the Odds Ratio and its confidence intervals (95 % CI) was measured and later a multivariate analysis was performed. Results: The sample was comprised of 87 patients (29 cases and 58 controls). The 68.96% of the cases (n=20) were male patients and their average age was 63.03 years. People with history of alcohol consumption showed a 16 times greater risk (OR=16.03). Poor oral hygiene (OR: 5.23; CI 95%: 1.18-23.29; p=0.030) and traumatic irritants (OR: 4.41; CI 95 %: 1.01-19.23; p=0.048) were risk factors too. Conclusion: A strong association between the disease and the antecedent of alcohol consumption, the exposition to traumatic irritating and the poor oral hygiene was identified.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1401neoplasias de la bocacarcinoma de células escamosasfactores de riesgoepidemiología.
spellingShingle Ibraín Enrique Corrales-Reyes
Vanesa Cruz-Sánchez
Christian R. Mejia
Oral squamous cell carcinoma and associated risk factors: A case-control study
Revista Cubana de Medicina Militar
neoplasias de la boca
carcinoma de células escamosas
factores de riesgo
epidemiología.
title Oral squamous cell carcinoma and associated risk factors: A case-control study
title_full Oral squamous cell carcinoma and associated risk factors: A case-control study
title_fullStr Oral squamous cell carcinoma and associated risk factors: A case-control study
title_full_unstemmed Oral squamous cell carcinoma and associated risk factors: A case-control study
title_short Oral squamous cell carcinoma and associated risk factors: A case-control study
title_sort oral squamous cell carcinoma and associated risk factors a case control study
topic neoplasias de la boca
carcinoma de células escamosas
factores de riesgo
epidemiología.
url http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1401
work_keys_str_mv AT ibrainenriquecorralesreyes oralsquamouscellcarcinomaandassociatedriskfactorsacasecontrolstudy
AT vanesacruzsanchez oralsquamouscellcarcinomaandassociatedriskfactorsacasecontrolstudy
AT christianrmejia oralsquamouscellcarcinomaandassociatedriskfactorsacasecontrolstudy