Adhesive polyelectrolyte coating through UV-triggered polymerization on PLGA particles for enhanced drug delivery to inflammatory intestinal mucosa
Abstract Administering medication precisely to the inflamed intestinal sites to treat ulcerative colitis (UC), with minimized side effects, is of urgent need. In UC, the inflammation damaged mucosa contains a large number of amino groups which are positively charged, providing new opportunities for...
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Main Authors: | Jie Zhang, Yi-jing Yin, Xing-wang Wang, Wei-qi Lu, Zhao-yang Chen, Chao-hui Yu, Ke-feng Ren, Cheng-fu Xu |
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Format: | Article |
Language: | English |
Published: |
BMC
2025-01-01
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Series: | Journal of Nanobiotechnology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12951-024-03066-3 |
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