Lineage trajectories and fate determinants of postnatal neural stem cells and ependymal cells in the developing ventricular zone.

Lineage trajectories and fate determinants of postnatal neural stem cells and ependymal cells in the developing ventricular zone.

The ventricular zone (VZ) harbors the largest neurogenic niche in the adult mammalian brain and is consisted of neural stem cells (NSCs) and multiciliated ependymal cells (EPCs). Previous lineage tracing studies showed that both NSCs and EPCs were derived from radial glial cells (RGCs). However, the...

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Bibliographic Details
Main Authors: Jianqun Zheng, Yawen Chen, Yukun Hu, Yujian Zhu, Jie Lin, Manlin Xu, Yunlong Zhang, Weihong Song, Xi Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-07-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003318
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