Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report
Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has the pulmonary form as the most common presentation. Dissemination of the disease is common in immunocompromised patients, but immunodeficiency related to pregnancy severe enough to cause dissemination of the Mycoba...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2003-09-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500028&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849685278812274688 |
|---|---|
| author | Emerson L. Gasparetto Priscilla Tazoniero Arnolfo de Carvalho Neto |
| author_facet | Emerson L. Gasparetto Priscilla Tazoniero Arnolfo de Carvalho Neto |
| author_sort | Emerson L. Gasparetto |
| collection | DOAJ |
| description | Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has the pulmonary form as the most common presentation. Dissemination of the disease is common in immunocompromised patients, but immunodeficiency related to pregnancy severe enough to cause dissemination of the Mycobacteria is exceedingly rare. When dissemination occurs, any organ may be affected and in central nervous system, the infection presents as meningitis and single brain parenchyma tuberculomas. We report the case of a 17 year-old woman at the 34th week of pregnancy with respiratory and high intracranial pressure symptoms. On the day before admission she had a sudden onset of paraparesis and urinary retention and ten hours after the delivery she presented with paraplegia . The chest X-ray and CT scan were compatible with miliary tuberculosis. The cranial CT scan revealed numerous rounded hypodense lesions located at cerebral and cerebellar hemispheres, which presented ring-like enhancement after contrast injection. The patient underwent a craniotomy with biopsy of the lesions confirming the diagnosis of brain tuberculomas. The three-drug regimen was started and the cranial CT scan performed a year after diagnosis showed no brain lesions. We emphasize the aggressive dissemination of the disease in this case associated with pregnancy and the importance of early diagnosis and institution of therapy resulting in regression of the lesions. |
| format | Article |
| id | doaj-art-c385bd79407448e58f136bfff7eabaff |
| institution | DOAJ |
| issn | 1678-4227 |
| language | English |
| publishDate | 2003-09-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-c385bd79407448e58f136bfff7eabaff2025-08-20T03:23:12ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272003-09-01613B85585810.1590/S0004-282X2003000500028Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case reportEmerson L. Gasparetto0Priscilla Tazoniero1Arnolfo de Carvalho Neto2Universidade Federal do ParanáUniversidade Federal do ParanáUniversidade Federal do ParanáTuberculosis is an infectious disease caused by Mycobacterium tuberculosis, which has the pulmonary form as the most common presentation. Dissemination of the disease is common in immunocompromised patients, but immunodeficiency related to pregnancy severe enough to cause dissemination of the Mycobacteria is exceedingly rare. When dissemination occurs, any organ may be affected and in central nervous system, the infection presents as meningitis and single brain parenchyma tuberculomas. We report the case of a 17 year-old woman at the 34th week of pregnancy with respiratory and high intracranial pressure symptoms. On the day before admission she had a sudden onset of paraparesis and urinary retention and ten hours after the delivery she presented with paraplegia . The chest X-ray and CT scan were compatible with miliary tuberculosis. The cranial CT scan revealed numerous rounded hypodense lesions located at cerebral and cerebellar hemispheres, which presented ring-like enhancement after contrast injection. The patient underwent a craniotomy with biopsy of the lesions confirming the diagnosis of brain tuberculomas. The three-drug regimen was started and the cranial CT scan performed a year after diagnosis showed no brain lesions. We emphasize the aggressive dissemination of the disease in this case associated with pregnancy and the importance of early diagnosis and institution of therapy resulting in regression of the lesions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500028&tlng=encentral nervous systemtuberculosispregnancytuberculoma |
| spellingShingle | Emerson L. Gasparetto Priscilla Tazoniero Arnolfo de Carvalho Neto Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report Arquivos de Neuro-Psiquiatria central nervous system tuberculosis pregnancy tuberculoma |
| title | Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report |
| title_full | Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report |
| title_fullStr | Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report |
| title_full_unstemmed | Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report |
| title_short | Disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas: case report |
| title_sort | disseminated tuberculosis in a pregnant woman presenting with numerous brain tuberculomas case report |
| topic | central nervous system tuberculosis pregnancy tuberculoma |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2003000500028&tlng=en |
| work_keys_str_mv | AT emersonlgasparetto disseminatedtuberculosisinapregnantwomanpresentingwithnumerousbraintuberculomascasereport AT priscillatazoniero disseminatedtuberculosisinapregnantwomanpresentingwithnumerousbraintuberculomascasereport AT arnolfodecarvalhoneto disseminatedtuberculosisinapregnantwomanpresentingwithnumerousbraintuberculomascasereport |