Antioxidant Properties and Bioactivity of Streptomyces albus DR57
The bioactive molecules found in Streptomyces are important due to their potential applications in medicine, particularly in combating infections and cancer. Studies have identified various bioactive compounds produced by different Streptomyces strains, highlighting their diverse therapeutic propert...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Journal of Pure and Applied Microbiology
2025-03-01
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| Series: | Journal of Pure and Applied Microbiology |
| Subjects: | |
| Online Access: | https://microbiologyjournal.org/antioxidant-properties-and-bioactivity-of-streptomyces-albus-dr57/ |
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| Summary: | The bioactive molecules found in Streptomyces are important due to their potential applications in medicine, particularly in combating infections and cancer. Studies have identified various bioactive compounds produced by different Streptomyces strains, highlighting their diverse therapeutic properties. Streptomyces albus is a prolific source of bioactive molecules, producing a diverse array of secondary metabolites with significant pharmaceutical potential. This study aimed to identify the bioactive components of Streptomyces strains isolated from marine sediment and assess their antioxidant properties. The experimental study was designed based on standard protocols to isolate Streptomyces strain from starch casein, which was further confirmed using 16S rRNA sequencing. The extracellular products from the strain were extracted using ethyl acetate and a high-efficiency vacuum evaporator to identify the active molecules using GC-MS. The antioxidant properties of the crude extract, including total phenol content, absolute antioxidant capacity, free radical neutralization power, and overall reducing power, were evaluated. All experiments were conducted in triplicate. Mean values with standard deviation were reported, and the isolated strain was identified as Streptomyces albus DR 57. In addition to eight primary active extracellular compounds, diethyl phthalate and glycyl-L-proline were detected in this strain. Research has indicated that glycyl-L-proline possesses various therapeutic potentials. The phenolic compound (22.23 ± 0.37 µg/mL) identified in this strain serves as the principal element responsible for its antioxidant characteristics. This study concluded that the identified strain demonstrated significant antioxidant capabilities. Further investigation is required to understand the mechanisms involved and to enhance the extraction of these beneficial compounds for practical applications. |
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| ISSN: | 0973-7510 2581-690X |