Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity

Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity

Summary: Factors influencing the macrophage surfaceome define macrophage identity and behavior. Here, we use genome-wide phenotypic screens to identify genes affecting the accessibility and surface expression of macrophage signal regulatory protein alpha (SIRPA). Our data are consistent with previou...

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Bibliographic Details
Main Authors: Adrian Granda Farias, Brian Feng, Shahbaz Khan, Wayne Ngo, Jamie L.Y. Wu, Magali Aguilera-Uribe, Shan Grewal, Patricia Mero, Sheila K. Singh, Thomas Kislinger, Warren C.W. Chan, Jason Moffat
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124725006928
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