ECSIT‐X4 is Required for Preventing Pressure Overload‐Induced Cardiac Hypertrophy via Regulating Mitochondrial STAT3

ECSIT‐X4 is Required for Preventing Pressure Overload‐Induced Cardiac Hypertrophy via Regulating Mitochondrial STAT3

Abstract Mitochondrial dysfunction is a key factor in exacerbating pressure overload‐induced cardiac hypertrophy and is linked to increased morbidity and mortality. ECSIT, a crucial adaptor for inflammation and mitochondrial function, has been reported to express multiple transcripts in various spec...

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Main Authors: Xia Lu, Tingting Tong, Haoliang Sun, Yi Chen, Yongfeng Shao, Pengxi Shi, Linli Que, Li Liu, Guoqing Zhu, Qi Chen, Chuanfu Li, Jiantao Li, Shuo Yang, Yuehua Li
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
cardiac hypertrophy
ECSIT‐X4
mitochondria
STAT3
Online Access:https://doi.org/10.1002/advs.202414358
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