Long noncoding RNA GAS5 acts as a competitive endogenous RNA to regulate GSK-3β and PTEN expression by sponging miR-23b-3p in Alzheimer’s disease

Long noncoding RNA GAS5 acts as a competitive endogenous RNA to regulate GSK-3β and PTEN expression by sponging miR-23b-3p in Alzheimer’s disease

Long noncoding RNA and microRNA are regulatory noncoding RNAs that are implicated in Alzheimer’s disease, but the role of long noncoding RNA-associated competitive endogenous RNA has not been fully elucidated. The long noncoding RNA growth arrest-specific 5 (GAS5) is a member of the 5′-terminal olig...

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Bibliographic Details
Main Authors: Li Zeng, Kaiyue Zhao, Jianghong Liu, Mimin Liu, Zhongdi Cai, Ting Sun, Zhuorong Li, Rui Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2026-01-01
Series:Neural Regeneration Research
Subjects:
alzheimer’s disease
amyloid-beta peptide accumulation
cognitive dysfunction
competitive endogenous rna
glycogen synthase kinase 3beta
lncrna growth arrest-specific 5
microrna-23b-3p
neuronal apoptosis
phosphatase and tensin homologue deleted on chromosome 10
tau phosphorylation
Online Access:https://journals.lww.com/10.4103/NRR.NRR-D-23-01273
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