Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer
A cascaded optic-reflector sensing system combining a microfiber interferometer (MFI) and a gold-coated tilted fiber Bragg grating (TFBG) is proposed for detecting progesterone (PG) concentration. The sensor uses molecularly imprinted polymers (MIP) as a recognition layer and metal-organic framework...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-07-01
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| Series: | Food Chemistry: X |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2590157525005899 |
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| author | Hanlin Liu Miao Liu Shuyuan Guo Jingru Mao Yongfeng Zou Yuejiang Yu Dandan Sun Jie Ma |
| author_facet | Hanlin Liu Miao Liu Shuyuan Guo Jingru Mao Yongfeng Zou Yuejiang Yu Dandan Sun Jie Ma |
| author_sort | Hanlin Liu |
| collection | DOAJ |
| description | A cascaded optic-reflector sensing system combining a microfiber interferometer (MFI) and a gold-coated tilted fiber Bragg grating (TFBG) is proposed for detecting progesterone (PG) concentration. The sensor uses molecularly imprinted polymers (MIP) as a recognition layer and metal-organic frameworks (MOFs) for enhanced sensitivity. The remove and rebind of PG will both cause changes in the local refractive index (RI) on MFI, and these changes can be monitored by the intensity variations on TFBG. Experimental results show a detection range of 10−6–20 μg/ml, with a sensitivity of 41,837 dB/(μg/ml) and a limit of detection (LOD) of 10−6 μg/ml. Simultaneously, it has been established that the sensor has good specificity in ten different real samples. This cascaded structure reflective sensor provides a simple and reliable technology for the quantitative detection of PG concentration in dairy products and water. |
| format | Article |
| id | doaj-art-c3364ead457c4d689a7ad8353cd0b66f |
| institution | Kabale University |
| issn | 2590-1575 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry: X |
| spelling | doaj-art-c3364ead457c4d689a7ad8353cd0b66f2025-08-20T03:50:22ZengElsevierFood Chemistry: X2590-15752025-07-012910274210.1016/j.fochx.2025.102742Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymerHanlin Liu0Miao Liu1Shuyuan Guo2Jingru Mao3Yongfeng Zou4Yuejiang Yu5Dandan Sun6Jie Ma7School of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, ChinaSchool of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; Shanxi Key Laboratory of Wireless Communication and Detection, Shanxi University, Taiyuan 030006, China; Corresponding author at: School of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China.School of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China; State Key Laboratory of Quantum Optics and Quantum Optics Devices, Institute of Laser Spectroscopy, Shanxi University, Taiyuan 030006, China; Collaborative Innovation Center of Extreme Optics, Shanxi University, Taiyuan 030006, China; Corresponding author at: School of Physics and Electronic Engineering, Shanxi University, Taiyuan 030006, China.A cascaded optic-reflector sensing system combining a microfiber interferometer (MFI) and a gold-coated tilted fiber Bragg grating (TFBG) is proposed for detecting progesterone (PG) concentration. The sensor uses molecularly imprinted polymers (MIP) as a recognition layer and metal-organic frameworks (MOFs) for enhanced sensitivity. The remove and rebind of PG will both cause changes in the local refractive index (RI) on MFI, and these changes can be monitored by the intensity variations on TFBG. Experimental results show a detection range of 10−6–20 μg/ml, with a sensitivity of 41,837 dB/(μg/ml) and a limit of detection (LOD) of 10−6 μg/ml. Simultaneously, it has been established that the sensor has good specificity in ten different real samples. This cascaded structure reflective sensor provides a simple and reliable technology for the quantitative detection of PG concentration in dairy products and water.http://www.sciencedirect.com/science/article/pii/S2590157525005899Microfiber interferometerTilted fiber Bragg gratingMolecularly imprinted polymerMetal-organic frameworkProgesterone |
| spellingShingle | Hanlin Liu Miao Liu Shuyuan Guo Jingru Mao Yongfeng Zou Yuejiang Yu Dandan Sun Jie Ma Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer Food Chemistry: X Microfiber interferometer Tilted fiber Bragg grating Molecularly imprinted polymer Metal-organic framework Progesterone |
| title | Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer |
| title_full | Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer |
| title_fullStr | Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer |
| title_full_unstemmed | Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer |
| title_short | Advanced optic-fiber sensor for progesterone concentration detection relying on the temperature-compensated reflective structure functionalized with molecularly imprinted polymer |
| title_sort | advanced optic fiber sensor for progesterone concentration detection relying on the temperature compensated reflective structure functionalized with molecularly imprinted polymer |
| topic | Microfiber interferometer Tilted fiber Bragg grating Molecularly imprinted polymer Metal-organic framework Progesterone |
| url | http://www.sciencedirect.com/science/article/pii/S2590157525005899 |
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