What an Interventionalist Needs to Know About INOCA

Ischaemia with non-obstructed coronary artery disease (INOCA) remains a diagnostic and therapeutic challenge. An anatomical investigation-based approach to ischaemic heart disease fails to account for disorders of vasomotion. The main INOCA endotypes are microvascular angina, vasospastic angina, mix...

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Main Authors: Daniel Tze Yee Ang, Colin Berry
Format: Article
Language:English
Published: Radcliffe Medical Media 2021-12-01
Series:Interventional Cardiology: Reviews, Research, Resources
Online Access:https://www.icrjournal.com/articleindex/icr.2021.16
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author Daniel Tze Yee Ang
Colin Berry
author_facet Daniel Tze Yee Ang
Colin Berry
author_sort Daniel Tze Yee Ang
collection DOAJ
description Ischaemia with non-obstructed coronary artery disease (INOCA) remains a diagnostic and therapeutic challenge. An anatomical investigation-based approach to ischaemic heart disease fails to account for disorders of vasomotion. The main INOCA endotypes are microvascular angina, vasospastic angina, mixed (both) or non-cardiac symptoms. The interventional diagnostic procedure (IDP) enables differentiation between clinical endotypes, with linked stratified medical therapy leading to a reduced symptom burden and a better quality of life. Interventionists are therefore well placed to make a positive impact with more personalised care. Despite adjunctive tests of coronary function being supported by contemporary guidelines, IDP use in daily practice remains limited. More widespread adoption should be encouraged. This article reviews a stratified approach to INOCA, describes a streamlined approach to the IDP and highlights some practical and safety considerations.
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series Interventional Cardiology: Reviews, Research, Resources
spelling doaj-art-c332e80c5d3349afa6cdceaad2bfda1b2025-08-20T02:39:16ZengRadcliffe Medical MediaInterventional Cardiology: Reviews, Research, Resources1756-14771756-14852021-12-011610.15420/icr.2021.16What an Interventionalist Needs to Know About INOCADaniel Tze Yee Ang0Colin Berry1University of Glasgow, Glasgow, UK; Golden Jubilee National Hospital, Clydebank, UKUniversity of Glasgow, Glasgow, UK; Golden Jubilee National Hospital, Clydebank, UKIschaemia with non-obstructed coronary artery disease (INOCA) remains a diagnostic and therapeutic challenge. An anatomical investigation-based approach to ischaemic heart disease fails to account for disorders of vasomotion. The main INOCA endotypes are microvascular angina, vasospastic angina, mixed (both) or non-cardiac symptoms. The interventional diagnostic procedure (IDP) enables differentiation between clinical endotypes, with linked stratified medical therapy leading to a reduced symptom burden and a better quality of life. Interventionists are therefore well placed to make a positive impact with more personalised care. Despite adjunctive tests of coronary function being supported by contemporary guidelines, IDP use in daily practice remains limited. More widespread adoption should be encouraged. This article reviews a stratified approach to INOCA, describes a streamlined approach to the IDP and highlights some practical and safety considerations.https://www.icrjournal.com/articleindex/icr.2021.16
spellingShingle Daniel Tze Yee Ang
Colin Berry
What an Interventionalist Needs to Know About INOCA
Interventional Cardiology: Reviews, Research, Resources
title What an Interventionalist Needs to Know About INOCA
title_full What an Interventionalist Needs to Know About INOCA
title_fullStr What an Interventionalist Needs to Know About INOCA
title_full_unstemmed What an Interventionalist Needs to Know About INOCA
title_short What an Interventionalist Needs to Know About INOCA
title_sort what an interventionalist needs to know about inoca
url https://www.icrjournal.com/articleindex/icr.2021.16
work_keys_str_mv AT danieltzeyeeang whataninterventionalistneedstoknowaboutinoca
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