Few-Layer Graphene-Based Optical Nanobiosensors for the Early-Stage Detection of Ovarian Cancer Using Liquid Biopsy and an Active Learning Strategy

Few-Layer Graphene-Based Optical Nanobiosensors for the Early-Stage Detection of Ovarian Cancer Using Liquid Biopsy and an Active Learning Strategy

Ovarian cancer survival depends strongly on the time of diagnosis. Detection at stage 1 must be the goal of liquid biopsies for ovarian cancer detection. We report the development and validation of graphene-based optical nanobiosensors (G-NBSs) that quantify the activities of a panel of proteases, w...

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Bibliographic Details
Main Authors: Obdulia Covarrubias-Zambrano, Deepesh Agarwal, Joan Lewis-Wambi, Raul Neri, Andrea Jewell, Balasubramaniam Natarajan, Stefan H. Bossmann
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
Subjects:
graphene-based nanobiosensors
biomarkers
liquid biopsy
ovarian cancer detection
protease activity
biophotonics
Online Access:https://www.mdpi.com/2073-4409/14/5/375
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