Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis.

Synthetic heparan sulfate oligosaccharides inhibit endothelial cell functions essential for angiogenesis.

<h4>Background</h4>Heparan sulfate (HS) is an important regulator of the assembly and activity of various angiogenic signalling complexes. However, the significance of precisely defined HS structures in regulating cytokine-dependent angiogenic cellular functions and signalling through re...

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Main Authors: Claire L Cole, Steen U Hansen, Marek Baráth, Graham Rushton, John M Gardiner, Egle Avizienyte, Gordon C Jayson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-07-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0011644&type=printable
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