Functional activity of gdТ-cells in atopic dermatitis

Functional activity of gdТ-cells in atopic dermatitis (AD) in dependence on the disease stage and concomitant pathology character was studied. We investigated 86 patients: 54 women and 32 men aged 17—50 years. AD patients revealed significant insufficiency of the cell immunity, the most marked of th...

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Main Authors: Ye. G. Chourina, V. V. Klimov
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2006-06-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/3078
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author Ye. G. Chourina
V. V. Klimov
author_facet Ye. G. Chourina
V. V. Klimov
author_sort Ye. G. Chourina
collection DOAJ
description Functional activity of gdТ-cells in atopic dermatitis (AD) in dependence on the disease stage and concomitant pathology character was studied. We investigated 86 patients: 54 women and 32 men aged 17—50 years. AD patients revealed significant insufficiency of the cell immunity, the most marked of them being in gdТ-cells.The level of CD8aa did not differ practically but number of CD8ab-cells and NK-cells was decreased. Clinically, it manifested in continuously recurrent course of the disease with high risk of complications with joiningbacterial and viral infections.
format Article
id doaj-art-c311295717bd4d7e82773d0a75e327fe
institution Kabale University
issn 1682-0363
1819-3684
language English
publishDate 2006-06-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-c311295717bd4d7e82773d0a75e327fe2025-08-20T04:00:18ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842006-06-015213714010.20538/1682-0363-2006-2-137-1401736Functional activity of gdТ-cells in atopic dermatitisYe. G. Chourina0V. V. Klimov1Сибирский государственный медицинский университетСибирский государственный медицинский университетFunctional activity of gdТ-cells in atopic dermatitis (AD) in dependence on the disease stage and concomitant pathology character was studied. We investigated 86 patients: 54 women and 32 men aged 17—50 years. AD patients revealed significant insufficiency of the cell immunity, the most marked of them being in gdТ-cells.The level of CD8aa did not differ practically but number of CD8ab-cells and NK-cells was decreased. Clinically, it manifested in continuously recurrent course of the disease with high risk of complications with joiningbacterial and viral infections.https://bulletin.ssmu.ru/jour/article/view/3078атопический дерматитgdт-клеткиatopic dermatitisgdтcells
spellingShingle Ye. G. Chourina
V. V. Klimov
Functional activity of gdТ-cells in atopic dermatitis
Бюллетень сибирской медицины
атопический дерматит
gdт-клетки
atopic dermatitis
gdтcells
title Functional activity of gdТ-cells in atopic dermatitis
title_full Functional activity of gdТ-cells in atopic dermatitis
title_fullStr Functional activity of gdТ-cells in atopic dermatitis
title_full_unstemmed Functional activity of gdТ-cells in atopic dermatitis
title_short Functional activity of gdТ-cells in atopic dermatitis
title_sort functional activity of gdт cells in atopic dermatitis
topic атопический дерматит
gdт-клетки
atopic dermatitis
gdтcells
url https://bulletin.ssmu.ru/jour/article/view/3078
work_keys_str_mv AT yegchourina functionalactivityofgdtcellsinatopicdermatitis
AT vvklimov functionalactivityofgdtcellsinatopicdermatitis