Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort

Essential oil of Chinese medicinal herb, Ligusticum chuanxiong dried rhizome was found to possess insecticidal activity against maize weevils, Sitophilus zeamais. The main components of L. chuanxiong essential oil were Z-3-butylidenephthalide (20.56%), Z-ligustilide (19.61%), 4-terpinenol (8.82%), 4...

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Main Authors: Sha Sha Chu, Guo Hua Jiang, Zhi Long Liu
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2011/163760
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author Sha Sha Chu
Guo Hua Jiang
Zhi Long Liu
author_facet Sha Sha Chu
Guo Hua Jiang
Zhi Long Liu
author_sort Sha Sha Chu
collection DOAJ
description Essential oil of Chinese medicinal herb, Ligusticum chuanxiong dried rhizome was found to possess insecticidal activity against maize weevils, Sitophilus zeamais. The main components of L. chuanxiong essential oil were Z-3-butylidenephthalide (20.56%), Z-ligustilide (19.61%), 4-terpinenol (8.82%), 4-vinylguaiacol (6.81%) and α-selinene (6.01%). Bioactivity-guided chromatographic separation of the essential oil on repeated silica gel columns led to isolate three compounds namely 3-butylidenephthalide, Z-ligustilide and 4-vinylguaiacol. Z-liqustilide and Z-3-butylidenephthalide showed pronounced toxicity against S. zeamais (LD50= 10.23 and 15.81 μg/adult respectively) and were more toxic than 4-vinylguaiacol (LD50 = 63.75 μg/adult). The crude essential oil also possessed contact toxicity against S. zeamais (LD50 = 13.09 μg/adult).
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spelling doaj-art-c3097885445e4e4f96c959a5d6866ef32025-08-20T03:23:15ZengWileyE-Journal of Chemistry0973-49452090-98102011-01-018130030410.1155/2011/163760Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong HortSha Sha Chu0Guo Hua Jiang1Zhi Long Liu2Department of Entomology, China Agricultural University Yuanmingyuan West Road, Haidian District, Beijing 100094, ChinaThe Analytic and Testing CenterBeijing Normal University, Beijing 100875, ChinaDepartment of Entomology, China Agricultural University Yuanmingyuan West Road, Haidian District, Beijing 100094, ChinaEssential oil of Chinese medicinal herb, Ligusticum chuanxiong dried rhizome was found to possess insecticidal activity against maize weevils, Sitophilus zeamais. The main components of L. chuanxiong essential oil were Z-3-butylidenephthalide (20.56%), Z-ligustilide (19.61%), 4-terpinenol (8.82%), 4-vinylguaiacol (6.81%) and α-selinene (6.01%). Bioactivity-guided chromatographic separation of the essential oil on repeated silica gel columns led to isolate three compounds namely 3-butylidenephthalide, Z-ligustilide and 4-vinylguaiacol. Z-liqustilide and Z-3-butylidenephthalide showed pronounced toxicity against S. zeamais (LD50= 10.23 and 15.81 μg/adult respectively) and were more toxic than 4-vinylguaiacol (LD50 = 63.75 μg/adult). The crude essential oil also possessed contact toxicity against S. zeamais (LD50 = 13.09 μg/adult).http://dx.doi.org/10.1155/2011/163760
spellingShingle Sha Sha Chu
Guo Hua Jiang
Zhi Long Liu
Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
E-Journal of Chemistry
title Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
title_full Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
title_fullStr Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
title_full_unstemmed Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
title_short Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort
title_sort insecticidal components from the essential oil of chinese medicinal herb ligusticum chuanxiong hort
url http://dx.doi.org/10.1155/2011/163760
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