Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds

ABSTRACT The spermosphere, the dynamic interface surrounding germinating seeds, is shaped by the intricate interplay between seed-exuded natural compounds and seed-associated microbial communities. In this work, we provide the first comprehensive metabolomic and microbiome characterization of common...

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Main Authors: Chandrodhay Saccaram, Marie Simonin, Stéphanie Boutet, Céline Brosse, Shuang Peng, Tracy François, Boris Collet, François Perreau, Delphine Sourdeval, Coralie Marais, Matthieu Barret, Loïc Rajjou, Massimiliano Corso
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:mSystems
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Online Access:https://journals.asm.org/doi/10.1128/msystems.00707-25
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author Chandrodhay Saccaram
Marie Simonin
Stéphanie Boutet
Céline Brosse
Shuang Peng
Tracy François
Boris Collet
François Perreau
Delphine Sourdeval
Coralie Marais
Matthieu Barret
Loïc Rajjou
Massimiliano Corso
author_facet Chandrodhay Saccaram
Marie Simonin
Stéphanie Boutet
Céline Brosse
Shuang Peng
Tracy François
Boris Collet
François Perreau
Delphine Sourdeval
Coralie Marais
Matthieu Barret
Loïc Rajjou
Massimiliano Corso
author_sort Chandrodhay Saccaram
collection DOAJ
description ABSTRACT The spermosphere, the dynamic interface surrounding germinating seeds, is shaped by the intricate interplay between seed-exuded natural compounds and seed-associated microbial communities. In this work, we provide the first comprehensive metabolomic and microbiome characterization of common bean (Phaseolus vulgaris) spermosphere of eight genotypes produced in two contrasted production regions. Through an integrated approach, we explored the metabolomic and microbiota composition in the spermosphere of germinating common bean seeds and elucidated their environmental and genotype regulation. We detected and analyzed 2,467 metabolite features (Mf) through untargeted metabolomics categorized into fourteen metabolic categories, highlighting the prevalence of amino acids, flavonoids, and terpenoids. Genotype was the key factor influencing the chemical composition of the spermosphere. Furthermore, we identified 19 bacterial families and 23 fungal families inhabiting the spermosphere, with both genotype and seed production location exerting varying degrees of influence on microbial community composition. Through a multiscale integrated approach, we revealed specific associations between metabolites and microorganisms, such as negative correlation between flavonoids and Bacillus spp., emphasizing the genotype-dependent nature of these interactions. This comprehensive investigation sheds light on the mechanisms underlying seed germination and the complex interactions between plant genotypes, seed exudates, environmental conditions, and microbial communities in the spermosphere. These findings provide a framework for developing innovative strategies to promote seed health and sustainable crop production.IMPORTANCEThe spermosphere, the dynamic interface around germinating seeds, is shaped by the intricate interplay between seed-exuded compounds and microbial communities. Despite the importance of these interactions for eventual seedling emergence and health, little knowledge is available on the subject. We are the first to comprehensively analyze the chemical and microbial diversity of the spermosphere of Phaseolus vulgaris (common bean). We identified thousands of primary and specialized metabolites, highlighting their diversity but largely unknown roles in germinating seed-environment interactions. We revealed significant genotype-driven differences in the chemical composition as well as the influence of both genotype and seed production location on microbial community structure in the spermosphere. Our metabolome-microbiome integrative analysis suggests that common bean shapes the spermosphere microbiome through specific seed exudates. This research advances our understanding of the metabolic capabilities and ecological roles of seed microbiota within the spermosphere, contributing to our understanding of seed health and vigor.
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spelling doaj-art-c2fefeddb6054b149e769d9096fa9e602025-08-20T03:47:16ZengAmerican Society for MicrobiologymSystems2379-50772025-08-0110810.1128/msystems.00707-25Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seedsChandrodhay Saccaram0Marie Simonin1Stéphanie Boutet2Céline Brosse3Shuang Peng4Tracy François5Boris Collet6François Perreau7Delphine Sourdeval8Coralie Marais9Matthieu Barret10Loïc Rajjou11Massimiliano Corso12Université Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceIRHS-UMR1345, Université d’Angers, INRAE, Institut Agro, Beaucouzé, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceIRHS-UMR1345, Université d’Angers, INRAE, Institut Agro, Beaucouzé, FranceIRHS-UMR1345, Université d’Angers, INRAE, Institut Agro, Beaucouzé, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceUniversité Paris-Saclay, INRAE, AgroParisTech, Institute Jean-Pierre Bourgin for Plant Sciences (IJPB), Versailles, FranceABSTRACT The spermosphere, the dynamic interface surrounding germinating seeds, is shaped by the intricate interplay between seed-exuded natural compounds and seed-associated microbial communities. In this work, we provide the first comprehensive metabolomic and microbiome characterization of common bean (Phaseolus vulgaris) spermosphere of eight genotypes produced in two contrasted production regions. Through an integrated approach, we explored the metabolomic and microbiota composition in the spermosphere of germinating common bean seeds and elucidated their environmental and genotype regulation. We detected and analyzed 2,467 metabolite features (Mf) through untargeted metabolomics categorized into fourteen metabolic categories, highlighting the prevalence of amino acids, flavonoids, and terpenoids. Genotype was the key factor influencing the chemical composition of the spermosphere. Furthermore, we identified 19 bacterial families and 23 fungal families inhabiting the spermosphere, with both genotype and seed production location exerting varying degrees of influence on microbial community composition. Through a multiscale integrated approach, we revealed specific associations between metabolites and microorganisms, such as negative correlation between flavonoids and Bacillus spp., emphasizing the genotype-dependent nature of these interactions. This comprehensive investigation sheds light on the mechanisms underlying seed germination and the complex interactions between plant genotypes, seed exudates, environmental conditions, and microbial communities in the spermosphere. These findings provide a framework for developing innovative strategies to promote seed health and sustainable crop production.IMPORTANCEThe spermosphere, the dynamic interface around germinating seeds, is shaped by the intricate interplay between seed-exuded compounds and microbial communities. Despite the importance of these interactions for eventual seedling emergence and health, little knowledge is available on the subject. We are the first to comprehensively analyze the chemical and microbial diversity of the spermosphere of Phaseolus vulgaris (common bean). We identified thousands of primary and specialized metabolites, highlighting their diversity but largely unknown roles in germinating seed-environment interactions. We revealed significant genotype-driven differences in the chemical composition as well as the influence of both genotype and seed production location on microbial community structure in the spermosphere. Our metabolome-microbiome integrative analysis suggests that common bean shapes the spermosphere microbiome through specific seed exudates. This research advances our understanding of the metabolic capabilities and ecological roles of seed microbiota within the spermosphere, contributing to our understanding of seed health and vigor.https://journals.asm.org/doi/10.1128/msystems.00707-25seedsspermospheregerminationmetabolomemicrobiomePhaseolus vulgaris
spellingShingle Chandrodhay Saccaram
Marie Simonin
Stéphanie Boutet
Céline Brosse
Shuang Peng
Tracy François
Boris Collet
François Perreau
Delphine Sourdeval
Coralie Marais
Matthieu Barret
Loïc Rajjou
Massimiliano Corso
Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
mSystems
seeds
spermosphere
germination
metabolome
microbiome
Phaseolus vulgaris
title Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
title_full Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
title_fullStr Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
title_full_unstemmed Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
title_short Elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean (Phaseolus vulgaris L.) seeds
title_sort elucidating the interplay between metabolites and microorganisms in the spermosphere of common bean phaseolus vulgaris l seeds
topic seeds
spermosphere
germination
metabolome
microbiome
Phaseolus vulgaris
url https://journals.asm.org/doi/10.1128/msystems.00707-25
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