Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment
Mycotoxins, as prevalent contaminants in the food chain, exhibit diverse toxicological effects on both animals and humans. Chronic dietary exposure to mycotoxin-contaminated foods may result in the bioaccumulation of these toxins, posing substantial public health risks. This review systematically ex...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-03-01
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| Series: | Foods |
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| Online Access: | https://www.mdpi.com/2304-8158/14/5/865 |
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| author | Kailin Li Hua Cai Baozhang Luo Shenggang Duan Jingjin Yang Nan Zhang Yi He Aibo Wu Hong Liu |
| author_facet | Kailin Li Hua Cai Baozhang Luo Shenggang Duan Jingjin Yang Nan Zhang Yi He Aibo Wu Hong Liu |
| author_sort | Kailin Li |
| collection | DOAJ |
| description | Mycotoxins, as prevalent contaminants in the food chain, exhibit diverse toxicological effects on both animals and humans. Chronic dietary exposure to mycotoxin-contaminated foods may result in the bioaccumulation of these toxins, posing substantial public health risks. This review systematically examines the contamination patterns of mycotoxins across major food categories, including cereals and related products, animal-derived foods, fruits, and medical food materials. Furthermore, we critically evaluated two methodological frameworks for assessing mycotoxin exposure risks: (1) dietary exposure models integrating contamination levels and consumption data and (2) human biomonitoring approaches quantifying mycotoxin biomarkers in biological samples. A key contribution lies in the stratified analysis of exposure disparities among population subgroups (adults, teenagers, children, and infants). Additionally, we summarize current research on the relationship between human mycotoxin biomonitoring and associated health impacts, with a particular emphasis on vulnerable groups such as pregnant women and infants. By elucidating the challenges inherent in existing studies, this synthesis provides a roadmap for advancing risk characterization and evidence-based food safety interventions. |
| format | Article |
| id | doaj-art-c2fdbac61a994aa7a1b8bef2c587e91a |
| institution | DOAJ |
| issn | 2304-8158 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj-art-c2fdbac61a994aa7a1b8bef2c587e91a2025-08-20T02:59:14ZengMDPI AGFoods2304-81582025-03-0114586510.3390/foods14050865Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk AssessmentKailin Li0Hua Cai1Baozhang Luo2Shenggang Duan3Jingjin Yang4Nan Zhang5Yi He6Aibo Wu7Hong Liu8Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaSIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200331, ChinaShanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, ChinaMycotoxins, as prevalent contaminants in the food chain, exhibit diverse toxicological effects on both animals and humans. Chronic dietary exposure to mycotoxin-contaminated foods may result in the bioaccumulation of these toxins, posing substantial public health risks. This review systematically examines the contamination patterns of mycotoxins across major food categories, including cereals and related products, animal-derived foods, fruits, and medical food materials. Furthermore, we critically evaluated two methodological frameworks for assessing mycotoxin exposure risks: (1) dietary exposure models integrating contamination levels and consumption data and (2) human biomonitoring approaches quantifying mycotoxin biomarkers in biological samples. A key contribution lies in the stratified analysis of exposure disparities among population subgroups (adults, teenagers, children, and infants). Additionally, we summarize current research on the relationship between human mycotoxin biomonitoring and associated health impacts, with a particular emphasis on vulnerable groups such as pregnant women and infants. By elucidating the challenges inherent in existing studies, this synthesis provides a roadmap for advancing risk characterization and evidence-based food safety interventions.https://www.mdpi.com/2304-8158/14/5/865contaminantshuman biomonitoringpopulation subgroupshealth effects |
| spellingShingle | Kailin Li Hua Cai Baozhang Luo Shenggang Duan Jingjin Yang Nan Zhang Yi He Aibo Wu Hong Liu Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment Foods contaminants human biomonitoring population subgroups health effects |
| title | Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment |
| title_full | Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment |
| title_fullStr | Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment |
| title_full_unstemmed | Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment |
| title_short | Recent Progress of Mycotoxin in Various Food Products—Human Exposure and Health Risk Assessment |
| title_sort | recent progress of mycotoxin in various food products human exposure and health risk assessment |
| topic | contaminants human biomonitoring population subgroups health effects |
| url | https://www.mdpi.com/2304-8158/14/5/865 |
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